FGF23

Gene Symbol	FGF23
Entrez Gene	8074
Alt Symbol	ADHR, FGFN, HPDR2, HYPF, PHPTC
Species	Human
Gene Type	protein-coding
Description	fibroblast growth factor 23
Other Description	phosphatonin|tumor-derived hypophosphatemia inducing factor
Swissprots	Q9GZV9 Q4V758
Accessions	AAP97433 AAS59157 CAI93447 CAT81644 CAT82838 CBX33262 EAW88848 Q9GZV9 AB037973 BAB13477 AB047858 BAB55889 AF263537 AAG09917 AY358323 AAQ88689 BC069333 AAH69333 BC096713 AAH96713 BC098147 AAH98147 BC098252 AAH98252 NM_020638 NP_065689
Function	Regulator of phosphate homeostasis. Inhibits renal tubular phosphate transport by reducing SLC34A1 levels. Upregulates EGR1 expression in the presence of KL (By similarity). Acts directly on the parathyroid to decrease PTH secretion (By similarity). Regulator of vitamin-D metabolism. Negatively regulates osteoblast differentiation and matrix mineralization. {ECO:0000250, ECO:0000269|PubMed:11062477, ECO:0000269|PubMed:11409890, ECO:0000269|PubMed:15040831, ECO:0000269|PubMed:16597617, ECO:0000269|PubMed:18282132}.
Subcellular Location	Secreted {ECO:0000269|PubMed:16638743}. Note=Secretion is dependent on O-glycosylation.
Tissue Specificity	Expressed in osteogenic cells particularly during phases of active bone remodeling. In adult trabecular bone, expressed in osteocytes and flattened bone-lining cells (inactive osteoblasts). {ECO:0000269|PubMed:12952917}.
Top Pathways	Melanoma, MAPK signaling pathway, PI3K-Akt signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human FGF23 ELISA Kit (Sandwich ELISA) - LS-F4428 from LifeSpan Bioscience Category ELISA Kit Prices $650.00 Sizes 1 plate Sensitivity 15.63 pg/ml Range 15.63-1000 pg/ml

Mouse FGF23 ELISA Kit (Sandwich ELISA) - LS-F6071 from LifeSpan Bioscience Category ELISA Kit Prices $670.00 Sizes 1 plate Sensitivity 15.63 pg/ml Range 15.63-1000 pg/ml

Rat FGF23 / FGF-23 ELISA Kit - LS-F5734 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 2.8 pg/ml Range 7.813 - 500 pg/ml

Rat FGF23 ELISA Kit (Sandwich ELISA) - LS-F11453 from LifeSpan Bioscience Category ELISA Kit Prices $530.00 Sizes 1 plate Sensitivity 15.6 Range 15.63-1000 pg/ml

Human FGF23 ELISA Kit (Sandwich ELISA) - LS-F11452 from LifeSpan Bioscience Category ELISA Kit Prices $530.00 Sizes 1 plate Sensitivity 15.6 pg/ml Range 15.63-1000 pg/ml

Human FGF-23 DuoSet ELISA - DY2604-05 from R&D Systems Category ELISA Kit Prices $299.00 Sizes 1 kit (for 5 Plates) Range 78.10 - 5,000 pg/mL

Human FGF23 ELISA Kit - abx151522 from Abbexa Category ELISA Kit Sensitivity 6.7 pg/ml Range 15.625 pg/ml - 1000 pg/ml

Human FGF23 ELISA Kit - abx056152 from Abbexa Category ELISA Kit

Human Fibroblast Growth Factor 23 ELISA Kit - abx053699 from Abbexa Category ELISA Kit Sensitivity 0.8 ng/L Range 4 ng/L -100 ng/L

Fibroblast Growth Factor 23, FGF23, Human, ELISA Kit - E-EL-H1116 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 9.375 Range 15.625-1000pg/mL

Fibroblast growth factor 23, FGF23, Human, ELISA Kit - E0746h from ARP American Research Products Category ELISA Kit Prices $476.00 Sizes 96 t Range 15.6-1000 pg/ml

Fibroblast growth factor 23, Human, ELISA Kit - E01F0009 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 0.1g/ml Range 0.5-10ng/ml

Fibroblast Growth Factor 23, FGF23, Rabbit, ELISA Kit - E-EL-RB0377 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 9.375 Range 15.625-1000pg/mL

Fibroblast Growth Factor 23, FGF23, Chicken, ELISA Kit - E-EL-Ch2200 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 9.375 Range 15.625-1000pg/mL

Fibroblast Growth Factor 23, FGF23, Porcine, ELISA Kit - E-EL-P0859 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 37.5 Range 62.5-4000pg/mL

Fibroblast Growth Factor 23, FGF23, Sheep, ELISA Kit - E-EL-S0599 from ARP American Research Products Category ELISA Kit Prices $648.00 Sizes 96 t

Fibroblast Growth Factor 23, FGF23, Guinea Pig, ELISA Kit - E-EL-GP0098 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Fibroblast Growth Factor 23, FGF23, Monkey, ELISA Kit - E-EL-MK1766 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Custom Human FGF-23 ELISA - ELH-FGF23 from RayBiotech Category ELISA Kit Prices $615.00, $1,107.00, $2,460.00 Sizes 1 plate kit, 2 plate kit, 5 plate kit

Human FGF-23 ELISA Kit - HF0016 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Anserine FGF-23 ELISA Kit - AF0016 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Fibroblast growth factor 23, ELISA Kit - MBS739598 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 1.0 pg/mL.

Fibroblast growth factor 23, ELISA Kit - MBS736531 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Fibroblast growth factor 23, ELISA Kit - MBS741661 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 1.0 pg/mL.

Fibroblast Growth Factor 23, ELISA Kit - MBS051747 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 5.0 pg/ml. Range 31.2 pg/ml - 1000 pg/ml.

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