ZRANB3

Gene Symbol ZRANB3
Entrez Gene 84083
Alt Symbol 4933425L19Rik, AH2
Species Human
Gene Type protein-coding
Description zinc finger, RAN-binding domain containing 3
Other Description DNA annealing helicase and endonuclease ZRANB3|annealing helicase 2|zinc finger Ran-binding domain-containing protein 3
Swissprots D3DP76 B5MDI3 Q53SM1 B3KYA1 Q9H0E8 B4E375 Q5FWF4 E9PBP0 Q8N1P4 Q6P2C4
Accessions AAX93066 AAY14765 EAX11629 EAX11630 EAX11631 EAX11632 EAX11633 EAX11634 EAX11635 EAX11636 Q5FWF4 AI670931 AK095362 BAC04536 AK131303 BAG54763 AK304601 BAG65387 AL136824 CAB66758 AL833322 AM392694 CAL37572 AM392702 CAL37580 BC089429 AAH89429 BX647838 XM_005263809 XP_005263866 XM_005263811 XP_005263868 XM_005263812 XP_005263869 XM_006712788 XP_006712851 XM_011511958 XP_011510260 XM_011511959 XP_011510261 XM_011511960 XP_011510262 XM_011511961 XP_011510263 XM_011511962 XP_011510264 XM_011511963 XP_011510265 XM_011511964 XP_011510266 XM_011511965 XP_011510267 XM_011511966 XP_011510268 XM_011511967 XP_011510269 NM_001286568 NP_001273497 NM_001286569 NP_001273498 NM_032143 NP_115519
Function DNA annealing helicase and endonuclease required to maintain genome stability at stalled or collapsed replication forks by facilitating fork restart and limiting inappropriate recombination that could occur during template switching events. Recruited to the sites of stalled DNA replication by polyubiquitinated PCNA and acts as a structure-specific endonuclease that cleaves the replication fork D-loop intermediate, generating an accessible 3'-OH group in the template of the leading strand, which is amenable to extension by DNA polymerase. In addition to endonuclease activity, also catalyzes the fork regression via annealing helicase activity in order to prevent disintegration of the replication fork and the formation of double-strand breaks. {ECO:0000269|PubMed:21078962, ECO:0000269|PubMed:22704558, ECO:0000269|PubMed:22705370, ECO:0000269|PubMed:22759634}.
Subcellular Location Nucleus. Chromosome. Note=Following DNA damage, recruited to sites of DNA damage and stalled replication forks by polyubiquitinated PCNA.

ZRANB3 (A-12) - sc-137957 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ZRANB3 (A-12): sc-137957. Western blot analysis of ZRANB3 expression in HeLa (A), Jurkat (B) and K-562 (C) whole cell lysates.

ZRANB3 (P-12) - sc-137959 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ZRANB3 (P-12): sc-137959. Western blot analysis of ZRANB3 expression in K-562 (A) and HeLa (B) whole cell lysates.

Anti-ZRANB3 antibody - ab109595 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-ZRANB3 antibody (ab109595) at 0.1 µg/mlLane 1 : 293T whole cell lysate at 50 µgLane 2 : 293T whole cell lysate at 15 µgLane 3 : 293T whole cell lysate at 5 µgLane 4 : HeLa whole cell lysate at 50 µgdeveloped using the ECL technique

Anti-ZRANB3 antibody - C-terminal - ab186972 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ZRANB3 Antibody (aa640-689) - LS-C206226 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-ZRANB3 Antibody (aa1029-1079) - LS-C289737 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human ZRANB3 by Western Blot and Immunoprecipitation. Samples: Whole cell lysate from 293T (5, 15 and 50 ug for WB; 1 mg for IP, 20% of IP loaded) and HeLa (H; 50 ug) cells. Antibodies: Affinity purified rabbit anti-ZRANB3 antibody used for WB at 0.1 ug/ml (A) and 1 ug/ml (B) and used for IP at 6 ug/mg lysate. ZRANB3 was also immunoprecipitated by rabbit anti-ZRANB3 antibody BL10989, which recognizes an upstream epitope. Detection: Chemiluminescence with exposure times of 3 minutes (A) and 30 seconds (B).

ZRANB3 Antibody - NBP2-13604 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: ZRANB3 Antibody [NBP2-13604] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10<br/>Lane 2: Human cell line RT-4<br/>Lane 3: Human cell line U-251MG sp<br/>Lane 4: Human plasma (IgG/HSA depleted)

ZRANB3 Antibody - NBP2-13605 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: ZRANB3 Antibody [NBP2-13605] - Staining of human cell line U-251 MG shows positivity in nucleus but not nucleoli & centrosome.

ZRANB3 Antibody - NBP1-52644 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: ZRANB3 Antibody [NBP1-52644] - Affinity purified rabbit anti-ZRANB3 antibody used for WB at 0.1 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 6 mcg/mg lysate. ZRANB3 was also immunoprecipitated by another rabbit anti-ZRANB3 antibody, which recognizes an upstream epitope.

Anti-ZRANB3 antibody produced in rabbit - HPA043301 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-ZRANB3:<B>Cat. No. HPA043301</B>: Immunohistochemical staining of human uterus, pre-menopause shows strong cytoplasmic and membranous positivity in glandular cells.

ZRANB3 Antibody - C-terminal region (ARP73294_P050) - ARP73294_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ZRANB3 antibody - 23111-1-AP from Acris Antibodies

Prices $270.00
Sizes 150 µl
Host Rabbit
Clonality Polyclonal
HEK-293 cells were subjected to SDS PAGE followed by western blot with 23111-1-AP( ZRANB3 Antibody) at dilution of 1:600

ZRANB3 antibody - 23111-1-AP from Proteintech Group

Prices $279.00
Sizes con: 53 μg/150μl
Host Rabbit
Clonality Polyclonal
HEK-293 cells were subjected to SDS PAGE followed by western blot with 23111-1-AP( ZRANB3 Antibody) at dilution of 1:600

ZRANB3 Antibody - A303-033A from Bethyl Labs

Prices $99.00, $229.00, $339.00
Sizes 20 µl (2 blots), 100 µl (10 blots), 100 µl (1 mg/ml)
Host Rabbit
Clonality Polyclonal

ZRANB3 Antibody - C-terminal region (ARP60544_P050) - ARP60544_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ZRANB3-Antibody-C-terminal-region-AI16075 - AI16075 from Abgent, a WuXi AppTec company

Prices $293.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Host: Rabbit Target Name: ZRANB3 Sample Tissue: MCF7 Whole Cell lysates Antibody Dilution: 1.0ug/ml

ZRANB3 - A9555 from NeoScientific

Prices $480.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

ZRANB3 Polyclonal Antibody - A9555 from ABclonal

Prices $130.00, $220.00, $380.00
Sizes 50 µl, 100 µl, 200 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using ZRANB3 antibody.

Anti-ZRANB3 antibody produced in rabbit - HPA043073 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-ZRANB3:<B>Cat. No. HPA043073</B>: Immunohistochemical staining of human stomach, upper shows strong cytoplasmic positivity in glandular cells.

ZRANB3 Antibody - abx124822 from Abbexa

Host Rabbit
Clonality Polyclonal

ZRANB3 antibody - orb186520 from Biorbyt

Prices $255.00, $340.00
Sizes 100 μg, 200 μg
Host Rabbit
Clonality Polyclonal

ZRANB3 Antibody,Biotin conjugated - CSB-PA705058LD01HU from Cusabio

Host Rabbit
Clonality Polyclonal

ZRANB3 Antibody,FITC conjugated - CSB-PA705058LC01HU from Cusabio

Host Rabbit
Clonality Polyclonal

ZRANB3 Antibody,HRP conjugated - CSB-PA705058LB01HU from Cusabio

Host Rabbit
Clonality Polyclonal

ZRANB3 Antibody - CSB-PA705058LA01HU from Cusabio

Host Rabbit
Clonality Polyclonal
Search more