PON1

Gene Symbol	PON1
Entrez Gene	5444
Alt Symbol	ESA, MVCD5, PON
Species	Human
Gene Type	protein-coding
Description	paraoxonase 1
Other Description	A-esterase 1|K-45|PON 1|aromatic esterase 1|arylesterase 1|arylesterase B-type|esterase A|paraoxonase B-type|serum aryldiakylphosphatase|serum aryldialkylphosphatase 1|serum paraoxonase/arylesterase 1
Swissprots	Q16052 B2RA40 Q9UCB1 P27169 Q6B0J6
Accessions	AAB25717 AAB27899 AAB41835 AAC35293 AAD02576 AAL04502 AAL04503 AAL04504 AAM97935 ACA53454 AEO20077 EAL24133 EAW76771 P27169 AK314027 BAG36737 AV652982 BC074719 AAH74719 BJ993711 CB122285 D84371 BAA12327 M63012 AAB59538 M63013 AAA60142 M63014 AAA60143 S64615 AAB27714 U53784 AAA97957 Z70723 CAA94728 NM_000446 NP_000437
Function	Hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. Capable of hydrolyzing a broad spectrum of organophosphate substrates and lactones, and a number of aromatic carboxylic acid esters. Mediates an enzymatic protection of low density lipoproteins against oxidative modification and the consequent series of events leading to atheroma formation. {ECO:0000269|PubMed:10479665, ECO:0000269|PubMed:15772423}.
Subcellular Location	Secreted, extracellular space.
Tissue Specificity	Plasma, associated with HDL (at protein level). Expressed in liver, but not in heart, brain, placenta, lung, skeletal muscle, kidney or pancreas. {ECO:0000269|PubMed:8292612, ECO:0000269|PubMed:8382160}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human PON1 ORF clone(NM_000446.5) - CDCL185770 from Creative Biomart Species Human Accession NM_000446.5

Human PON1 ORF clone(NM_000446.5) - CDCG013480 from Creative Biomart Species Human Accession NM_000446.5

Human PON1 Gene ORF cDNA clone in cloning vector - HG13083-G from Sino Biological Species Human

Human PON1 Gene ORF cDNA clone expression plasmid - HG13083-UT from Sino Biological Species Human

Human PON1 Gene ORF cDNA clone expression plasmid, C-HA tag - HG13083-CY from Sino Biological Species Human

Human PON1 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG13083-NF from Sino Biological Species Human

Human PON1 Gene ORF cDNA clone expression plasmid, N-HA tag - HG13083-NY from Sino Biological Species Human

Human PON1 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG13083-NM from Sino Biological Species Human

Human PON1 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG13083-CF from Sino Biological Species Human

Human PON1 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG13083-ACG from Sino Biological Species Human

Human PON1 Gene ORF cDNA clone expression plasmid, N-His tag - HG13083-NH from Sino Biological Species Human

Human PON1 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG13083-CM from Sino Biological Species Human

Human PON1 Gene ORF cDNA clone expression plasmid, C-His tag - HG13083-CH from Sino Biological Species Human

Human PON1 ORF clone(NM_000446.5) - CDCL185770 from Creative biogene Species Human

Human PON1 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG13083-ACR from Sino Biological Species Human

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