PON1

Gene Symbol PON1
Entrez Gene 5444
Alt Symbol ESA, MVCD5, PON
Species Human
Gene Type protein-coding
Description paraoxonase 1
Other Description A-esterase 1|K-45|PON 1|aromatic esterase 1|arylesterase 1|arylesterase B-type|esterase A|paraoxonase B-type|serum aryldiakylphosphatase|serum aryldialkylphosphatase 1|serum paraoxonase/arylesterase 1
Swissprots Q16052 B2RA40 Q9UCB1 P27169 Q6B0J6
Accessions AAB25717 AAB27899 AAB41835 AAC35293 AAD02576 AAL04502 AAL04503 AAL04504 AAM97935 ACA53454 AEO20077 EAL24133 EAW76771 P27169 AK314027 BAG36737 AV652982 BC074719 AAH74719 BJ993711 CB122285 D84371 BAA12327 M63012 AAB59538 M63013 AAA60142 M63014 AAA60143 S64615 AAB27714 U53784 AAA97957 Z70723 CAA94728 NM_000446 NP_000437
Function Hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. Capable of hydrolyzing a broad spectrum of organophosphate substrates and lactones, and a number of aromatic carboxylic acid esters. Mediates an enzymatic protection of low density lipoproteins against oxidative modification and the consequent series of events leading to atheroma formation. {ECO:0000269|PubMed:10479665, ECO:0000269|PubMed:15772423}.
Subcellular Location Secreted, extracellular space.
Tissue Specificity Plasma, associated with HDL (at protein level). Expressed in liver, but not in heart, brain, placenta, lung, skeletal muscle, kidney or pancreas. {ECO:0000269|PubMed:8292612, ECO:0000269|PubMed:8382160}.

PON1 CRISPR/Cas9 KO Plasmid (h) - sc-402701 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PON1 HDR Plasmid (h) - sc-402701-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PON1 Double Nickase Plasmid (h) - sc-402701-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PON1 Double Nickase Plasmid (h2) - sc-402701-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PON1 CRISPR Activation Plasmid (h) - sc-402701-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PON1 CRISPR Activation Plasmid (h2) - sc-402701-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PON1 Lentiviral Activation Particles (h) - sc-402701-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PON1 Lentiviral Activation Particles (h2) - sc-402701-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PON1 siRNA (h) - sc-44031 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PON1 shRNA Plasmid (h) - sc-44031-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PON1 shRNA (h) Lentiviral Particles - sc-44031-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PON1 RNAi - H00005444-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU044511 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN1711 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1711 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

PON1 siRNA (Human) - CRH3647 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human PON1 (NM_000446.5) - SHH379780 from Creative biogene

Category siRNA
Species Reactivities Human

PON1 shRNA Plasmid (Human) - CHH3647 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PON1 miRNA 3'UTR clone - MiUTR3H-01678 from Creative biogene

Species Reactivities Human
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