PON1

Gene Symbol PON1
Entrez Gene 5444
Alt Symbol ESA, MVCD5, PON
Species Human
Gene Type protein-coding
Description paraoxonase 1
Other Description A-esterase 1|K-45|PON 1|aromatic esterase 1|arylesterase 1|arylesterase B-type|esterase A|paraoxonase B-type|serum aryldiakylphosphatase|serum aryldialkylphosphatase 1|serum paraoxonase/arylesterase 1
Swissprots Q16052 B2RA40 Q9UCB1 P27169 Q6B0J6
Accessions AAB25717 AAB27899 AAB41835 AAC35293 AAD02576 AAL04502 AAL04503 AAL04504 AAM97935 ACA53454 AEO20077 EAL24133 EAW76771 P27169 AK314027 BAG36737 AV652982 BC074719 AAH74719 BJ993711 CB122285 D84371 BAA12327 M63012 AAB59538 M63013 AAA60142 M63014 AAA60143 S64615 AAB27714 U53784 AAA97957 Z70723 CAA94728 NM_000446 NP_000437
Function Hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. Capable of hydrolyzing a broad spectrum of organophosphate substrates and lactones, and a number of aromatic carboxylic acid esters. Mediates an enzymatic protection of low density lipoproteins against oxidative modification and the consequent series of events leading to atheroma formation. {ECO:0000269|PubMed:10479665, ECO:0000269|PubMed:15772423}.
Subcellular Location Secreted, extracellular space.
Tissue Specificity Plasma, associated with HDL (at protein level). Expressed in liver, but not in heart, brain, placenta, lung, skeletal muscle, kidney or pancreas. {ECO:0000269|PubMed:8292612, ECO:0000269|PubMed:8382160}.

Human PON1 full length protein - ab175468 from Abcam

Category Protein
Source E. coli
Species Human
12% SDS-PAGE analysis of ab175468 Lane 1: reduced and boiled sample (2.5 μg) Lane 2: non-reduced and non-boiled sample (2.5 μg)

Human PON1 full length protein - ab53376 from Abcam

Category Protein
Source E. coli
Species Human
SDS Page analysis of ab53376.

TACSTD1 / EPCAM Antibody Blocking Peptide - LS-E5589 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

TACSTD1 / EPCAM Antibody Blocking Peptide - LS-E7840 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

PON1 / ESA Antibody Blocking Peptide - LS-E406 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

PON1 / ESA Antibody Blocking Peptide - LS-E27034 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

PON1 / ESA Antibody Blocking Peptide - LS-E15230 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

PON1 Recombinant Protein - P3822 from Novus Biologicals

Category Protein
Prices $369.00
Sizes 10 µg
Species Human

Recombinant Human PON1 Protein - H00005444-Q01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

PON1-Antibody-Center-Blocking-peptide - BP10684c from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

PON1 blocking peptide - GTX88446-PEP from GeneTex

Category Peptide
Prices $239.00
Sizes 100 μg
Species Human

PON1 Protein (OPPA01520) - OPPA01520 from Aviva Systems Biology

Category Protein
Prices $100.00
Sizes 2 µg
Source E. Coli

Paraoxonase 1 (Western Blot Control) Protein (OPRB00133) - OPRB00133 from Aviva Systems Biology

Category Protein
Prices $249.00
Sizes 10 µg

Paraoxonase 1 Protein (OPRB00134) - OPRB00134 from Aviva Systems Biology

Category Protein
Prices $249.00
Sizes 10 µg

Paraoxonase 1 Protein (OPRB00135) - OPRB00135 from Aviva Systems Biology

Category Protein
Prices $839.00
Sizes 100 µg

Paraoxonase 1 (Mammalian) Protein (OPRB00238) - OPRB00238 from Aviva Systems Biology

Category Protein
Prices $449.00
Sizes 10 units/ml

Human PON1 protein - orb244453 from Biorbyt

Category Protein
Prices $213.00, $408.00, $680.00, $1,122.00, $1,777.00
Sizes 10 μg, 50 μg, 200 μg, 500 μg, 1 mg
Species Human

Human Paraoxonase-1 protein - orb90232 from Biorbyt

Category Protein
Prices $230.00, $442.00
Sizes 2 μg, 10 μg
Source E.coli
Species Human

PON1 Blocking Peptide - 33R-9864 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

PON1 Blocking Peptide - 33R-1504 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

Human Paraoxonase 1 Protein - abx068421 from Abbexa

Category Protein
Source E.coli
Species Human

PON1 Peptide - AC21-1857-P from Abcore

Category Peptide
Prices $160.00
Sizes 100 µg

PON1 - H00005444-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

PON1 - H00005444-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

PON1 - P3822 from Acris Antibodies

Category Protein
Prices $370.00
Sizes 10 µg
Species Human
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