UBE2M

Gene Symbol	UBE2M
Entrez Gene	9040
Alt Symbol	UBC-RS2, UBC12, hUbc12
Species	Human
Gene Type	protein-coding
Description	ubiquitin-conjugating enzyme E2M
Other Description	NEDD8 carrier protein|NEDD8 protein ligase|NEDD8-conjugating enzyme Ubc12|ubiquitin carrier protein M|ubiquitin-conjugating enzyme E2M (UBC12 homolog, yeast)|ubiquitin-protein ligase M|yeast UBC12 homolog
Swissprots	P61081
Accessions	CDM22105 EAW72612 EAW72613 P61081 AB012191 BAA33145 AF075599 AAC26141 AL569047 BC058924 AAH58924 BM559596 BM798750 BT006754 AAP35400 BU508830 BX342697 NM_003969 NP_003960
Function	Accepts the ubiquitin-like protein NEDD8 from the UBA3- NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX1, but not RBX2, suggests that the RBX1-UBE2M complex neddylates specific target proteins, such as CUL1, CUL2, CUL3 and CUL4. Involved in cell proliferation. {ECO:0000269|PubMed:10207026, ECO:0000269|PubMed:15361859}.
Top Pathways	Ubiquitin mediated proteolysis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

UBE2M-Over-expression-Lysate - LY11934a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

UBE2M 293 Cell Lysate - 408540 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

UBE2M/Ubc12 Overexpression Lysate (Native) - NBL1-17540 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

UBC12 (h): 293T Lysate - sc-116642 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

UBE2M Over-expression Lysate Product - GWB-C71A20 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

Panoply™ Human UBE2M Knockdown Stable Cell Line - CSC-DC016966 from Creative biogene Category Cell Line Species Human

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