UBE2M

Gene Symbol UBE2M
Entrez Gene 9040
Alt Symbol UBC-RS2, UBC12, hUbc12
Species Human
Gene Type protein-coding
Description ubiquitin-conjugating enzyme E2M
Other Description NEDD8 carrier protein|NEDD8 protein ligase|NEDD8-conjugating enzyme Ubc12|ubiquitin carrier protein M|ubiquitin-conjugating enzyme E2M (UBC12 homolog, yeast)|ubiquitin-protein ligase M|yeast UBC12 homolog
Swissprots P61081
Accessions CDM22105 EAW72612 EAW72613 P61081 AB012191 BAA33145 AF075599 AAC26141 AL569047 BC058924 AAH58924 BM559596 BM798750 BT006754 AAP35400 BU508830 BX342697 NM_003969 NP_003960
Function Accepts the ubiquitin-like protein NEDD8 from the UBA3- NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX1, but not RBX2, suggests that the RBX1-UBE2M complex neddylates specific target proteins, such as CUL1, CUL2, CUL3 and CUL4. Involved in cell proliferation. {ECO:0000269|PubMed:10207026, ECO:0000269|PubMed:15361859}.
Top Pathways Ubiquitin mediated proteolysis

UBC12 CRISPR/Cas9 KO Plasmid (h) - sc-403119 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

UBC12 HDR Plasmid (h) - sc-403119-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

UBC12 Double Nickase Plasmid (h) - sc-403119-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

UBC12 Double Nickase Plasmid (h2) - sc-403119-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

UBC12 CRISPR Activation Plasmid (h) - sc-403119-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

UBC12 CRISPR Activation Plasmid (h2) - sc-403119-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

UBC12 Lentiviral Activation Particles (h) - sc-403119-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

UBC12 Lentiviral Activation Particles (h2) - sc-403119-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

UBC12 siRNA (h) - sc-76786 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

UBC12 shRNA Plasmid (h) - sc-76786-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

UBC12 shRNA (h) Lentiviral Particles - sc-76786-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU046461 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN22373 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22373 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

UBE2M siRNA (Human) - CRH5963 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

UBE2M/Ubc12 RNAi - H00009040-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

UBE2M - MBS829310 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human UBE2M(NM_003969.3) - SHL110106 from Creative biogene

Category siRNA
Species Reactivities Human

UBE2M shRNA Plasmid (Human) - CHH5963 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

UBE2M miRNA 3'UTR clone - MiUTR1H-10953 from Creative biogene

Species Reactivities Human
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