UBE2M

Gene Symbol	UBE2M
Entrez Gene	9040
Alt Symbol	UBC-RS2, UBC12, hUbc12
Species	Human
Gene Type	protein-coding
Description	ubiquitin-conjugating enzyme E2M
Other Description	NEDD8 carrier protein|NEDD8 protein ligase|NEDD8-conjugating enzyme Ubc12|ubiquitin carrier protein M|ubiquitin-conjugating enzyme E2M (UBC12 homolog, yeast)|ubiquitin-protein ligase M|yeast UBC12 homolog
Swissprots	P61081
Accessions	CDM22105 EAW72612 EAW72613 P61081 AB012191 BAA33145 AF075599 AAC26141 AL569047 BC058924 AAH58924 BM559596 BM798750 BT006754 AAP35400 BU508830 BX342697 NM_003969 NP_003960
Function	Accepts the ubiquitin-like protein NEDD8 from the UBA3- NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX1, but not RBX2, suggests that the RBX1-UBE2M complex neddylates specific target proteins, such as CUL1, CUL2, CUL3 and CUL4. Involved in cell proliferation. {ECO:0000269|PubMed:10207026, ECO:0000269|PubMed:15361859}.
Top Pathways	Ubiquitin mediated proteolysis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human UBE2M full length protein - ab128447 from Abcam Category Protein Source E. coli Species Human

Human UBE2M full length protein - ab185866 from Abcam Category Protein Source E. coli Species Human

UBE2M protein (His tag) - ab127395 from Abcam Category Protein Source E. coli Species Human

UBE2M / UBC12 Antibody Blocking Peptide - LS-E15836 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human UBE2M/Ubc12 His (N-Term) Protein - NBP2-35116 from Novus Biologicals Category Protein Prices $69.00, $105.00, $1,969.00 Sizes 5 µg, 20 µg, 1 mg Source E. coli Species Human

UBE2M/Ubc12 Recombinant Protein - H00009040-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human UBE2M/Ubc12 Protein - NBP1-98926 from Novus Biologicals Category Protein Prices $269.00, $729.00 Sizes 100 µg, 500 µg Source E. coli Species Human

Recombinant Human UBE2M/Ubc12, CF - E2-656-050 from R&D Systems Category Protein Source E. coli-derived,

Recombinant Human UBE2M/Ubc12, CF - E2-656-100 from R&D Systems Category Protein Source E. coli-derived,

Recombinant Human GST-UBE2M/Ubc12, CF - E2-655-050 from R&D Systems Category Protein Source E. coli-derived, Contains an N-terminal GST (glutathione S-transferase) tag

Recombinant Human GST-UBE2M/Ubc12, CF - E2-655-100 from R&D Systems Category Protein Source E. coli-derived, Contains an N-terminal GST (glutathione S-transferase) tag

UBE2M Protein (OPPA00862) - OPPA00862 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 5 µg Source E. Coli

Human UBC12 protein - orb82784 from Biorbyt Category Protein Prices $1,853.00 Sizes 1 mg Source E.coli

Human Ubiquitin Conjugating Enzyme E2M protein - orb90005 from Biorbyt Category Protein Prices $221.00, $357.00, $425.00, $629.00 Sizes 10 μg, 50 μg, 100 μg, 250 μg Source E.coli

Human UBE2M protein - orb180352 from Biorbyt Category Protein Prices $179.00, $289.00, $791.00, $1,207.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Source E.coli Species Human

Human UBE2M protein - orb169511 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Species Human

Human UBE2M protein - orb139844 from Biorbyt Category Protein Prices $196.00, $298.00 Sizes 50 μg, 100 μg Source E. coli Species Human

UBE2M Blocking Peptide - 33R-4026 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

UBE2M protein (His tag) - 80R-2343 from Fitzgerald Category Protein Prices $270.00 Sizes 100 µg Source E.coli

UBE2M (1-183, His-tag) - AR50427PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

UBE2M (1-183, His-tag) - AR50427PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

UBE2M - H00009040-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

UBE2M - H00009040-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Ubiquitin Conjugating Enzyme E2M, Human Recombinant - 228-11589-1 from RayBiotech Category Protein Prices $118.00 Sizes 1 µg Source Escherichia Coli. Species Human

Recombinant Human UBE2M - 228-11589-2 from RayBiotech Category Protein Prices $189.00 Sizes 2 µg Source Escherichia Coli. Species Human

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