EXT2

Gene Symbol	EXT2
Entrez Gene	2132
Alt Symbol	SOTV
Species	Human
Gene Type	protein-coding
Description	exostosin glycosyltransferase 2
Other Description	N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase|exostosin-2|glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase|multiple exostoses protein 2|putative tumor suppressor protein EXT2
Swissprots	O15288 J3KPT2 C9JU51 Q93063 B2R5Z6
Accessions	AAC51219 EAW68067 EAW68068 EAW68069 EAW68070 EAW68071 Q93063 AK296713 BAH12417 AK309459 AK312375 BAG35293 BC010058 AAH10058 BC013050 BC068545 AAH68545 BE348865 BM997250 BX648142 DA738392 JF432315 ADZ15532 U62740 AAB07008 U64511 AAC50764 U72263 AAB62718 XM_011519950 XP_011518252 XM_011519951 XP_011518253 NM_000401 NP_000392 NM_001178083 NP_001171554 NM_207122 NP_997005
Function	Glycosyltransferase required for the biosynthesis of heparan-sulfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Appears to be a tumor suppressor.
Subcellular Location	Endoplasmic reticulum membrane {ECO:0000269|PubMed:10679296}; Single-pass type II membrane protein {ECO:0000269|PubMed:10679296}. Golgi apparatus membrane {ECO:0000269|PubMed:10679296}; Single-pass type II membrane protein {ECO:0000269|PubMed:10679296}. Note=The EXT1/EXT2 complex is localized in the Golgi apparatus.
Tissue Specificity	Ubiquitous.
Top Pathways	Glycosaminoglycan biosynthesis - heparan sulfate / heparin

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

EXT2 - MBS1266632 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC010058

Human EXT2 cDNA clone(NM_207122.1) - CDFG013753 from Creative Biomart Species Human Accession NM_207122.1

Human EXT2 cDNA clone(NM_001178083.1) - CDFH006222 from Creative Biomart Species Human Accession NM_001178083.1

Human EXT2 ORF Clone(NM_207122.1) - CDCR327893 from Creative Biomart Species Human Accession NM_207122.1

Human EXT2 ORF Clone(NM_207122.1) - CDCR327894 from Creative Biomart Species Human Accession NM_207122.1

Human EXT2 ORF Clone(NM_001178083.1) - CDCR357275 from Creative Biomart Species Human Accession NM_001178083.1

Human EXT2 ORF Clone(NM_001178083.1) - CDCR357279 from Creative Biomart Species Human Accession NM_001178083.1

Human EXT2 ORF Clone(NM_207122.1) - CDCR327893 from Creative biogene Species Human

Human EXT2 ORF clone (NM_001178083.1) - CDCR061964 from Creative biogene Species Human

Human EXT2 ORF clone (NM_000401.3) - CDCR061966 from Creative biogene Species Human

Human EXT2 ORF Clone (BC010058) - CDCS405639 from Creative biogene Species Human Accession Q93063

Human EXT2 cDNA Clone(NM_207122.1) - CDFG013753 from Creative biogene Species Human

Human EXT2 cDNA Clone(NM_001178083.1) - CDFH006222 from Creative biogene Species Human

Human EXT2 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG15016-CF from Sino Biological Species Human

Human EXT2 Gene ORF cDNA clone in cloning vector - HG15016-G from Sino Biological Species Human

Human EXT2 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG15016-NM from Sino Biological Species Human

Human EXT2 Gene ORF cDNA clone expression plasmid, N-His tag - HG15016-NH from Sino Biological Species Human

Human EXT2 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG15016-ACR from Sino Biological Species Human

Human EXT2 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG15016-ACG from Sino Biological Species Human

Human EXT2 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG15016-CM from Sino Biological Species Human

Human EXT2 Gene ORF cDNA clone expression plasmid, N-HA tag - HG15016-NY from Sino Biological Species Human

Human EXT2 Gene ORF cDNA clone expression plasmid, C-HA tag - HG15016-CY from Sino Biological Species Human

Human EXT2 Gene ORF cDNA clone expression plasmid, C-His tag - HG15016-CH from Sino Biological Species Human

Human EXT2 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG15016-NF from Sino Biological Species Human

Human EXT2 Gene ORF cDNA clone expression plasmid - HG15016-UT from Sino Biological Species Human

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