EXT2

Gene Symbol EXT2
Entrez Gene 2132
Alt Symbol SOTV
Species Human
Gene Type protein-coding
Description exostosin glycosyltransferase 2
Other Description N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase|exostosin-2|glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase|multiple exostoses protein 2|putative tumor suppressor protein EXT2
Swissprots O15288 J3KPT2 C9JU51 Q93063 B2R5Z6
Accessions AAC51219 EAW68067 EAW68068 EAW68069 EAW68070 EAW68071 Q93063 AK296713 BAH12417 AK309459 AK312375 BAG35293 BC010058 AAH10058 BC013050 BC068545 AAH68545 BE348865 BM997250 BX648142 DA738392 JF432315 ADZ15532 U62740 AAB07008 U64511 AAC50764 U72263 AAB62718 XM_011519950 XP_011518252 XM_011519951 XP_011518253 NM_000401 NP_000392 NM_001178083 NP_001171554 NM_207122 NP_997005
Function Glycosyltransferase required for the biosynthesis of heparan-sulfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Appears to be a tumor suppressor.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000269|PubMed:10679296}; Single-pass type II membrane protein {ECO:0000269|PubMed:10679296}. Golgi apparatus membrane {ECO:0000269|PubMed:10679296}; Single-pass type II membrane protein {ECO:0000269|PubMed:10679296}. Note=The EXT1/EXT2 complex is localized in the Golgi apparatus.
Tissue Specificity Ubiquitous.
Top Pathways Glycosaminoglycan biosynthesis - heparan sulfate / heparin

EXT2 (C-17) - sc-11045 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
EXT2 (C-17): sc-11045. Western blot analysis of EXT2 expression in non-transfected: sc-117752 (A) and mouse EXT2 transfected: sc-126818 (B) 293T whole cell lysates.

EXT2 (H-136) - sc-367877 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

EXT2 (N-15) - sc-11042 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-Ext2 antibody - ab102843 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-Ext2 antibody (ab102843) at 2 µg/ml + MDA-MB468 cell lysate at 35 µg

Anti-Ext2 antibody - ab54711 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Western blot against tagged recombinant protein immunogen using ab54711 Ext2 antibody at 1ug/ml.

Anti-EXT2 Antibody (aa182-209) - LS-C167866 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human brain tissue reacted with EXT2 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Anti-EXT2 Antibody (aa698-710) - LS-C112662 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-EXT2 Antibody (aa182-209, APC) - LS-C214067 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-EXT2 Antibody (aa182-209, AP) - LS-C214068 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-EXT2 Antibody (aa182-209, Biotin) - LS-C214069 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-EXT2 Antibody (aa182-209, FITC) - LS-C214070 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-EXT2 Antibody (aa182-209, Azide-free, HRP) - LS-C214071 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-EXT2 Antibody (aa182-209, PE) - LS-C214072 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-EXT2 Antibody - LS-C310299 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-EXT2 Antibody (aa188-218) - LS-C321232 from LifeSpan Bioscience

Prices $435.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-EXT2 Antibody (aa164-213) - LS-C102086 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
EXT2 antibody LS-C102086 Western blot of 721_B cell lysate.

Anti-EXT2 Antibody (clone 3G6) - LS-C197172 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3G6
EXT2 monoclonal antibody (M01), clone 3G6. Western Blot analysis of EXT2 expression in human spleen.

Anti-EXT2 Antibody (C-Terminus) - LS-C345335 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of EXT2 Antibody with human Placenta lysate.

Ext2 Antibody - NBP2-29948 from Novus Biologicals

Prices $299.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Ext2 Antibody [NBP2-29948] - Western blot analysis of lysate from T47D cell line,using EXT2 Antibody (Center)(NBP2-29948).AP9401c was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysate at 35ug per lane.

Ext2 Antibody - NBP1-58297 from Novus Biologicals

Prices $369.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western Blot: Ext2 Antibody [NBP1-58297] - 721_B cell lysate, concentration 0.2-1 ug/ml.

Ext2 Antibody - NBP2-33625 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: Ext2 Antibody [NBP2-33625] - Staining of duodenum.

Ext2 Antibody - 24860002 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Ext2 Antibody - NBP1-52137 from Novus Biologicals

Prices $229.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Ext2 Antibody (3G6) - H00002132-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3G6

Ext2 Antibody - H00002132-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: Ext2 Antibody [H00002132-B01] - analysis of EXT2 expression in transfected 293T cell line by EXT2 MaxPab polyclonal antibody (B01). Lane 1: EXT2 transfected lysate (82.30 KDa). Lane 2: Non-transfected lysate.
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