Gene Symbol | ABHD5 |
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Entrez Gene | 51099 |
Alt Symbol | CDS, CGI58, IECN2, NCIE2 |
Species | Human |
Gene Type | protein-coding |
Description | abhydrolase domain containing 5 |
Other Description | 1-acylglycerol-3-phosphate O-acyltransferase ABHD5|abhydrolase domain-containing protein 5|lipid droplet-binding protein CGI-58 |
Swissprots | B2R9K0 Q8WTS1 Q9Y369 |
Accessions | AEB53058 AEB53059 AEB53060 AEB53061 CAD12731 EAW64699 Q8WTS1 AF007132 AF151816 AAD34053 AK313811 BAG36547 BC021958 AAH21958 BG721387 DQ891175 ABM82101 DQ894357 ABM85283 XM_011533779 XP_011532081 XM_011533780 XP_011532082 XR_940447 NM_016006 NP_057090 |
Function | Lysophosphatidic acid acyltransferase which functions in phosphatidic acid biosynthesis. May regulate the cellular storage of triacylglycerol through activation of the phospholipase PNPLA2. Involved in keratinocyte differentiation. {ECO:0000269|PubMed:16679289, ECO:0000269|PubMed:18606822, ECO:0000269|PubMed:18832586}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:18832586}. Lipid droplet {ECO:0000250}. Note=Colocalized with PLIN and ADRP on the surface of lipid droplets. The localization is dependent upon the metabolic status of the adipocytes and the activity of PKA (By similarity). {ECO:0000250}. |
Tissue Specificity | Widely expressed in various tissues, including lymphocytes, liver, skeletal muscle and brain. Expressed by upper epidermal layers and dermal fibroblasts in skin, hepatocytes and neurons (at protein level). {ECO:0000269|PubMed:11590543, ECO:0000269|PubMed:18832586}. |
Human Abhd5 full length protein - ab132557 from Abcam
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Human Abhd5 peptide - ab89382 from Abcam
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Human Abhd5 protein fragment - ab153329 from Abcam
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Human Abhd5 protein fragment - ab153330 from Abcam
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ABHD5 Antibody Blocking Peptide - LS-E26280 from LifeSpan Bioscience
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ABHD5 Antibody Blocking Peptide - LS-E15628 from LifeSpan Bioscience
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ABHD5 Antibody Blocking Peptide - LS-E15629 from LifeSpan Bioscience
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Abhd5 Blocking Peptide - NB110-41576PEP from Novus Biologicals
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Recombinant Human Abhd5 Protein - H00051099-Q03 from Novus Biologicals
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Recombinant Human Abhd5 Protein - H00051099-P01 from Novus Biologicals
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Recombinant Human Abhd5 Protein - H00051099-Q01 from Novus Biologicals
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ABHD5 blocking peptide - GTX89147-PEP from GeneTex
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ABHD5 Blocking Peptide - 33R-6861 from Fitzgerald
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ABHD5 Blocking Peptide - 33R-8912 from Fitzgerald
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CGI58 Blocking Peptide - 33R-10990 from Fitzgerald
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ABHD5 Peptide - AC21-1112-P from Abcore
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ABHD5 - H00051099-P01-02 from Acris Antibodies
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ABHD5 - H00051099-Q01-10 from Acris Antibodies
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ABHD5 - H00051099-Q01-25 from Acris Antibodies
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ABHD5 - H00051099-Q03 from Acris Antibodies
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ABHD5 Peptide - 45-186P from ProSci
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ABHD5 fusion protein - Ag2840 from Proteintech Group
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Recombinant Human ABHD5, GST-tagged - ABHD5-9243H from Creative Biomart
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Recombinant Human 1-acylglycerol-3-phosphate O-acyltransferase ABHD5(ABHD5) - CSB-YP819884HU CSB-EP819884HU CSB-BP819884HU CSB-MP819884HU from Cusabio
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CGI-58 Blocking Peptide - 3901BP-50 from Biovision
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