Gene Symbol | ABHD5 |
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Entrez Gene | 51099 |
Alt Symbol | CDS, CGI58, IECN2, NCIE2 |
Species | Human |
Gene Type | protein-coding |
Description | abhydrolase domain containing 5 |
Other Description | 1-acylglycerol-3-phosphate O-acyltransferase ABHD5|abhydrolase domain-containing protein 5|lipid droplet-binding protein CGI-58 |
Swissprots | B2R9K0 Q8WTS1 Q9Y369 |
Accessions | AEB53058 AEB53059 AEB53060 AEB53061 CAD12731 EAW64699 Q8WTS1 AF007132 AF151816 AAD34053 AK313811 BAG36547 BC021958 AAH21958 BG721387 DQ891175 ABM82101 DQ894357 ABM85283 XM_011533779 XP_011532081 XM_011533780 XP_011532082 XR_940447 NM_016006 NP_057090 |
Function | Lysophosphatidic acid acyltransferase which functions in phosphatidic acid biosynthesis. May regulate the cellular storage of triacylglycerol through activation of the phospholipase PNPLA2. Involved in keratinocyte differentiation. {ECO:0000269|PubMed:16679289, ECO:0000269|PubMed:18606822, ECO:0000269|PubMed:18832586}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:18832586}. Lipid droplet {ECO:0000250}. Note=Colocalized with PLIN and ADRP on the surface of lipid droplets. The localization is dependent upon the metabolic status of the adipocytes and the activity of PKA (By similarity). {ECO:0000250}. |
Tissue Specificity | Widely expressed in various tissues, including lymphocytes, liver, skeletal muscle and brain. Expressed by upper epidermal layers and dermal fibroblasts in skin, hepatocytes and neurons (at protein level). {ECO:0000269|PubMed:11590543, ECO:0000269|PubMed:18832586}. |
ABHD5 (C-9) - sc-377270 from Santa Cruz Biotechnology
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ABHD5 (C-8) - sc-393949 from Santa Cruz Biotechnology
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ABHD5 (N-14) - sc-102286 from Santa Cruz Biotechnology
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ABHD5 (E-1) - sc-376931 from Santa Cruz Biotechnology
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ABHD5 (C-16) - sc-102285 from Santa Cruz Biotechnology
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ABHD5 (H-48) - sc-292546 from Santa Cruz Biotechnology
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ABHD5 (36A) - sc-100468 from Santa Cruz Biotechnology
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Anti-Abhd5 antibody - ab73551 from Abcam
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Anti-Abhd5 antibody - ab58283 from Abcam
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Anti-Abhd5 antibody - ab58275 from Abcam
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Anti-Abhd5 antibody [1F3] - ab118870 from Abcam
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Anti-Abhd5 antibody [EPR12621] - ab183739 from Abcam
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Anti-ABHD5 Antibody - LS-C335706 from LifeSpan Bioscience
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Anti-ABHD5 Antibody (clone 1F3) IHC-plus⢠- LS-B5751 from LifeSpan Bioscience
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Anti-ABHD5 Antibody (C-Terminus) IHC-plus⢠- LS-B3990 from LifeSpan Bioscience
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Anti-ABHD5 Antibody (aa181-192) IHC-plus⢠- LS-B4458 from LifeSpan Bioscience
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Anti-ABHD5 CGI58 Antibody (aa1-350, Azide-free) - LS-C121325 from LifeSpan Bioscience
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Anti-ABHD5 Antibody - LS-C125350 from LifeSpan Bioscience
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Anti-ABHD5 Antibody - LS-C147026 from LifeSpan Bioscience
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Anti-ABHD5 Antibody (aa101-150) - LS-C80506 from LifeSpan Bioscience
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Anti-ABHD5 Antibody (aa200-300) - LS-C49144 from LifeSpan Bioscience
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Abhd5 Antibody - NB110-41576 from Novus Biologicals
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Abhd5 Antibody (1F3) - H00051099-M01 from Novus Biologicals
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Abhd5 Antibody - NB100-57850 from Novus Biologicals
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Abhd5 Antibody - NBP1-55457 from Novus Biologicals
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