DNASE2B

Gene Symbol	DNASE2B
Entrez Gene	58511
Alt Symbol	DLAD
Species	Human
Gene Type	protein-coding
Description	deoxyribonuclease II beta
Other Description	DNase II beta|DNase II-like acid DNase|DNase2-like acid DNase|deoxyribonuclease-2-beta|endonuclease DLAD|lysosomal DNase II
Swissprots	Q5VXD0 Q8WZ80 Q5VXD1 Q9NQW3 Q8WZ79
Accessions	AAL34449 EAW73238 EAW73239 Q8WZ79 AF274571 AAF76893 AF333389 AAL34448 BC065182 BC080621 AAH80621 BC126136 AAI26137 BC126138 AAI26139 HQ258219 ADR82973 XM_011541878 XP_011540180 NM_021233 NP_067056 NM_058248 NP_490649
Function	Hydrolyzes DNA under acidic conditions. Does not require divalent cations for activity. Participates in the degradation of nuclear DNA during lens cell differentiation. {ECO:0000269|PubMed:11700027, ECO:0000269|PubMed:12944971}.
Subcellular Location	Lysosome {ECO:0000305}.
Tissue Specificity	Highly expressed in the eye lens and in salivary gland. Detected at lower levels in lung, prostate and lymph node. Isoform 2 is lung specific. {ECO:0000269|PubMed:11376952, ECO:0000269|PubMed:11700027, ECO:0000269|PubMed:12944971}.
Top Pathways	Lysosome

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human DNASE2B full length protein - ab163687 from Abcam Category Protein Source Wheat germ Species Human

Human DNASE2B protein fragment - ab163688 from Abcam Category Protein Source Wheat germ Species Human

DNASE2B Antibody Blocking Peptide - LS-E15683 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

DNASE2B Antibody Blocking Peptide - LS-E15685 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

DNASE2B Antibody Blocking Peptide - LS-E15684 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

DNASE2B Antibody Blocking Peptide - LS-E15686 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human DNASE2B Protein - H00058511-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human DNASE2B Protein - H00058511-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

DNASE2B Blocking Peptide - 33R-5727 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

DNASE2B Blocking Peptide - 33R-7604 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

DNASE2B Blocking Peptide - 33R-2433 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

DNASE2B Blocking Peptide - 33R-4011 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Deoxyribonuclease-2-beta - H00058511-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Deoxyribonuclease-2-beta - H00058511-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

Deoxyribonuclease-2-beta - H00058511-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Deoxyribonuclease-2-beta - H00058511-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

DNASE2B fusion protein - ag18246 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

DNASE2B fusion protein - ag18595 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Human Deoxyribonuclease-2-beta(DNASE2B) - CSB-YP841227HU CSB-EP841227HU CSB-BP841227HU CSB-MP841227HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Synthetic Human DNASE2B (aa 347-360)(CT) Blocking Peptide - PX025BP from Cell Science Category Peptide Prices $170.00 Sizes 50 μg Species Human

DNASE2B Peptide, Human - M34GP04452H from Creative Peptides Category Peptide Source Synthetic. Species Human

Deoxyribonuclease-2-beta (DNASE2B), Recombinant Protein - MBS1311273 from MyBioSource Category Protein Prices $1,095.00, $1,095.00, $1,325.00, $1,325.00, $1,725.00, $1,725.00, $2,190.00, $2,190.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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