DNASE2B

Gene Symbol	DNASE2B
Entrez Gene	58511
Alt Symbol	DLAD
Species	Human
Gene Type	protein-coding
Description	deoxyribonuclease II beta
Other Description	DNase II beta\|DNase II-like acid DNase\|DNase2-like acid DNase\|deoxyribonuclease-2-beta\|endonuclease DLAD\|lysosomal DNase II
Swissprots	Q5VXD0 Q8WZ80 Q5VXD1 Q9NQW3 Q8WZ79
Accessions	AAL34449 EAW73238 EAW73239 Q8WZ79 AF274571 AAF76893 AF333389 AAL34448 BC065182 BC080621 AAH80621 BC126136 AAI26137 BC126138 AAI26139 HQ258219 ADR82973 XM_011541878 XP_011540180 NM_021233 NP_067056 NM_058248 NP_490649
Function	Hydrolyzes DNA under acidic conditions. Does not require divalent cations for activity. Participates in the degradation of nuclear DNA during lens cell differentiation. {ECO:0000269\|PubMed:11700027, ECO:0000269\|PubMed:12944971}.
Subcellular Location	Lysosome {ECO:0000305}.
Tissue Specificity	Highly expressed in the eye lens and in salivary gland. Detected at lower levels in lung, prostate and lymph node. Isoform 2 is lung specific. {ECO:0000269\|PubMed:11376952, ECO:0000269\|PubMed:11700027, ECO:0000269\|PubMed:12944971}.
Top Pathways	Lysosome

DNASE2B (H-81) - sc-366674 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Rabbit
Clonality	Polyclonal

DNASE2B (S-13) - sc-131922 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

DNASE2B (S-22) - sc-101941 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	100 µg/ml
Host	Rabbit
Clonality	Polyclonal

DNASE2B (S-22): sc-101941. Western blot analysis of DNASE2B expression in Hep G2 whole cell lysate.

Anti-DNASE2B Antibody (aa47-96) - LS-C31907 from LifeSpan Bioscience

Prices	$325.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-DNASE2B Antibody (aa36-85) - LS-C101978 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

DNASE2B antibody LS-C101978 Western blot of Fetal Muscle lysate.

Anti-DNASE2B Antibody (aa288-337) - LS-C101979 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

DNASE2B antibody LS-C101979 Western blot of Placenta lysate.

Anti-DNASE2B Antibody (C-Terminus) - LS-C110703 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

DNASE2B antibody LS-C110703 Western blot of 293T cell lysate.

DNASE2B Antibody - NBP2-16199 from Novus Biologicals

Prices	$329.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Western Blot: DNASE2B Antibody [NBP2-16199] - Sample (30 ug of whole cell lysate) A: A549 12% SDS PAGE gel, diluted at 1:1000.

DNASE2B Antibody - NBP1-62279 from Novus Biologicals

Prices	$139.00, $329.00
Sizes	20 µl, 100 µl
Host	Rabbit
Clonality	Polyclonal

Western Blot: DNASE2B Antibody [NBP1-62279] - Human Placenta lysate, concentration 0.2-1 ug/ml.

DNASE2B Antibody - NBP1-69308 from Novus Biologicals

Prices	$329.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Western Blot: DNASE2B Antibody [NBP1-69308] - This Anti-DNASE2B antibody was used in Western Blot of Fetal Muscle tissue lysate at a concentration of 1ug/ml.

DNASE2B Antibody - H00058511-A01 from Novus Biologicals

Prices	$269.00
Sizes	50 µl
Host	Mouse
Clonality	Polyclonal

Anti-DNASE2B (ab1) antibody produced in rabbit - SAB2100608 from Sigma-Aldrich

Prices	$347.50
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

<B>Immunoblotting</B><BR/>Anti-DNASE2B (ab1): <B>Cat. No.SAB2100608</B>: DNASE2B in Fetal Muscle tissue lysate with DNASE2B antibody at 1.0 μg/mL.

Anti-DNASE2B (ab2) antibody produced in rabbit - SAB2100609 from Sigma-Aldrich

Prices	$347.50
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

<B>Immunoblotting</B><BR/>Anti-DNASE2B (ab2): <B>Cat. No.SAB2100609</B>: DNASE2B in 293T cell lysate with DNASE2B antibody at 1.0 μg/mL.

Anti-DNASE2B (ab3) antibody produced in rabbit - SAB2100610 from Sigma-Aldrich

Prices	$347.50
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

<B>Immunoblotting</B><BR/>Anti-DNASE2B (ab3): <B>Cat. No.SAB2100610</B>: DNASE2B in Placenta tissue lysate with DNASE2B antibody at 1.0 μg/mL.

Anti-DNASE2B antibody produced in rabbit - AV42595 from Sigma-Aldrich

Prices	$267.50
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

<B>Immunoblotting</B><BR/>Cell Type: Jurkat (<B>Cat. No. AV42595</B>).<BR/><B>Lanes</B><BR/>1. Antibody dilution (concentration) 1.25 μg/mL in cell type Jurkat

DNASE2B antibody - N-terminal region (ARP42593_P050) - ARP42593_P050 from Aviva Systems Biology

Prices	$289.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

DNASE2B antibody - C-terminal region (ARP42595_T100) - ARP42595_T100 from Aviva Systems Biology

Prices	$229.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

DNASE2B antibody - middle region (ARP42596_P050) - ARP42596_P050 from Aviva Systems Biology

Prices	$289.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

DNASE2B antibody - middle region (ARP42597_P050) - ARP42597_P050 from Aviva Systems Biology

Prices	$289.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

DNASE2B antibody [N1C3] - GTX119205 from GeneTex

Prices	$119.00
Sizes	25 μl
Host	Rabbit
Clonality	Polyclonal

Anti-DNASE2B antibody [N1C3] used in ICC/IF. GTX119205

DNASE2B antibody [N2C3] - GTX119206 from GeneTex

Prices	$119.00
Sizes	25 μl
Host	Rabbit
Clonality	Polyclonal

Anti-DNASE2B antibody [N2C3] used in Western blot. GTX119206

DNASE2B antibody - 70R-7163 from Fitzgerald

Prices	$345.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

DNASE2B antibody - 70R-7162 from Fitzgerald

Prices	$345.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

DNASE2B antibody - 70R-5280 from Fitzgerald

Prices	$345.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

DNASE2B antibody - 70R-1554 from Fitzgerald

Prices	$275.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

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