NR1H4

Gene Symbol	NR1H4
Entrez Gene	9971
Alt Symbol	BAR, FXR, HRR-1, HRR1, RIP14
Species	Human
Gene Type	protein-coding
Description	nuclear receptor subfamily 1, group H, member 4
Other Description	RXR-interacting protein 14|bile acid receptor|farnesoid X nuclear receptor|farnesoid X-activated receptor|farnesol receptor HRR-1|retinoid X receptor-interacting protein 14
Swissprots	A1L4K5 Q8NFP5 F8VYG8 B7ZM06 Q92943 Q8NFP6 B7Z412 Q96RI1
Accessions	EAW97638 EAW97639 EAW97640 Q96RI1 AB307699 BAH02290 AF384555 AAK60271 AF478445 AAM53550 AF478446 AAM53551 AK296612 BAH12398 AK296647 BAH12409 AK312959 BAG35798 BC035654 BC071778 AAH71778 BC130573 AAI30574 BC144183 BC144184 AAI44185 BC144187 BX571749 CAE11874 DA011411 HQ709175 ADZ17382 U68233 AAB08107 XM_006719719 XP_006719782 XM_011539040 XP_011537342 XM_011539041 XP_011537343 XM_011539042 XP_011537344 XR_245969 NM_001206977 NP_001193906 NM_001206978 NP_001193907 NM_001206979 NP_001193908 NM_001206992 NP_001193921 NM_001206993 NP_001193922 NM_005123 NP_005114
Function	Ligand-activated transcription factor. Receptor for bile acids such as chenodeoxycholic acid, lithocholic acid and deoxycholic acid. Represses the transcription of the cholesterol 7-alpha-hydroxylase gene (CYP7A1) through the induction of NR0B2 or FGF19 expression, via two distinct mechanisms. Activates the intestinal bile acid-binding protein (IBABP). Activates the transcription of bile salt export pump ABCB11 by directly recruiting histone methyltransferase CARM1 to this locus. {ECO:0000269|PubMed:10334992, ECO:0000269|PubMed:10334993, ECO:0000269|PubMed:12718892, ECO:0000269|PubMed:12815072, ECO:0000269|PubMed:15471871, ECO:0000269|PubMed:18621523, ECO:0000269|PubMed:19410460, ECO:0000269|PubMed:19586769}.
Subcellular Location	Nucleus {ECO:0000305}.
Top Pathways	Bile secretion

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human NR1H4 / FXR ELISA Kit (Sandwich ELISA) - LS-F5849 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.067 ng/ml Range 0.156-10 ng/ml

Mouse NR1H4 / FXR ELISA Kit (Sandwich ELISA) - LS-F7334 from LifeSpan Bioscience Category ELISA Kit Prices $740.00 Sizes 1 plate Sensitivity 0.051 ng/ml Range 0.156-10 ng/ml

Rat NR1H4 / FXR ELISA Kit (Sandwich ELISA) - LS-F8975 from LifeSpan Bioscience Category ELISA Kit Prices $780.00 Sizes 1 plate Sensitivity 0.053 ng/ml Range 0.156-10 ng/ml

Human NR1H4 / FXR ELISA Kit (Sandwich ELISA) - LS-F12188 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.156 Range 0.156-10 ng/ml

Bifunctional apoptosis regulator (BFAR), Human, ELISA Kit - CSB-EL002678HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Bile acid receptor (NR1H4), Human, ELISA Kit - E01B0957 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

Bile acid receptor, NR1H4, Human, ELISA Kit - E2042h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 0.156-10 ng/mL

Farnesoid X Receptor (FXR), Human, ELISA Kit - SEC042Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.067ng/mL Range 0.156-10ng/mL

Nuclear receptor subfamily 1, group H, member 4 (NR1H4), Human, ELISA Kit - E01N0563 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

Human FXR ELISA Kit - HF0272 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Anserine FXR ELISA Kit - AF0272 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Bile acid receptor (NR1H4), ELISA Kit - MBS7239180 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Bile acid receptor (NR1H4), ELISA Kit - MBS7227948 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Bile acid receptor (NR1H4), ELISA Kit - MBS7219009 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Bile acid receptor (NR1H4), ELISA Kit - MBS7216194 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Bile acid receptor (NR1H4), ELISA Kit - MBS7222339 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Bile acid receptor (NR1H4), ELISA Kit - MBS7238215 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Bile acid receptor (NR1H4), ELISA Kit - MBS7248967 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Bile acid receptor (NR1H4), ELISA Kit - MBS7251097 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Bile acid receptor (NR1H4), ELISA Kit - MBS7213250 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Bile acid receptor (NR1H4), ELISA Kit - MBS7200972 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Bile acid receptor (NR1H4), ELISA Kit - MBS7212238 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Bile acid receptor (NR1H4), ELISA Kit - MBS7220213 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Farnesoid X Receptor (FXR), ELISA Kit - MBS2021157 from MyBioSource Category ELISA Kit Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 0.067ng/mL. Range 0.156-10ng/mL

Farnesoid X Receptor (FXR), ELISA Kit - MBS2021232 from MyBioSource Category ELISA Kit

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