GPBAR1

Gene Symbol	GPBAR1
Entrez Gene	151306
Alt Symbol	BG37, GPCR19, GPR131, M-BAR, TGR5
Species	Human
Gene Type	protein-coding
Description	G protein-coupled bile acid receptor 1
Other Description	G-protein coupled bile acid receptor 1|G-protein coupled bile acid receptor BG37|G-protein coupled receptor GPCR19|hBG37|hGPCR19|membrane bile acid receptor|membrane-type receptor for bile acids
Swissprots	B3KV35 Q8TDU6
Accessions	BAB89314 CAD37291 CAD69712 EAW70598 Q8TDU6 AB086170 BAC65343 AB089307 BAC55235 AK122658 BAG53647 AK122660 BAG53648 BC033625 AAH33625 BI834364 DQ891340 ABM82266 DQ894522 ABM85448 XM_011510743 XP_011509045 XM_011510744 XP_011509046 NM_001077191 NP_001070659 NM_001077194 NP_001070662 NM_170699 NP_733800
Function	Receptor for bile acid. Bile acid-binding induces its internalization, activation of extracellular signal-regulated kinase and intracellular cAMP production. May be involved in the suppression of macrophage functions by bile acids. {ECO:0000269|PubMed:12419312, ECO:0000269|PubMed:12524422}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:12524422}; Multi-pass membrane protein {ECO:0000269|PubMed:12524422}.
Tissue Specificity	Ubiquitously expressed. Expressed at higher level in spleen and placenta. Expressed at lower level in other tissues. In digestive tissues, it is expressed in stomach, duodenum, ileocecum, ileum, jejunum, ascending colon, transverse colon, descending colon, cecum and liver, but not in esophagus and rectum. {ECO:0000269|PubMed:12044878, ECO:0000269|PubMed:12419312, ECO:0000269|PubMed:12524422}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

GPBAR1 overexpression lysate - LY406884 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

GPBAR1 overexpression lysate - LY421375 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

GPBAR1 overexpression lysate - LY421376 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

GPBAR1 overexpression lysate - LY425837 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

GPBAR1 overexpression lysate - LY430306 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

GPBAR1 293 Cell Lysate - 404058 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

GPBAR1 293 Cell Lysate - 409504 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

TGR5/GPBAR1 Overexpression Lysate (Native) - NBL1-11217 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

TGR5/GPBAR1 Overexpression Lysate (Native) - NBP2-05211 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

GPBAR1 Over-expression Lysate Product - GWB-DDEA8F from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

GPBAR1 Over-expression Lysate Product - GWB-AD0F10 from Genway Biotech Category Cell Lysate Prices $445.00 Sizes 100 µg Species Human

TGR5/GPBAR1 Overexpression Lysate (Native) - NBP2-11455 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

TGR5/GPBAR1 Overexpression Lysate (Native) - NBP2-10648 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

Panoply™ Human GPBAR1 Knockdown Stable Cell Line - CSC-DC006480 from Creative biogene Category Cell Line Species Human

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