GPBAR1

Gene Symbol	GPBAR1
Entrez Gene	151306
Alt Symbol	BG37, GPCR19, GPR131, M-BAR, TGR5
Species	Human
Gene Type	protein-coding
Description	G protein-coupled bile acid receptor 1
Other Description	G-protein coupled bile acid receptor 1|G-protein coupled bile acid receptor BG37|G-protein coupled receptor GPCR19|hBG37|hGPCR19|membrane bile acid receptor|membrane-type receptor for bile acids
Swissprots	B3KV35 Q8TDU6
Accessions	BAB89314 CAD37291 CAD69712 EAW70598 Q8TDU6 AB086170 BAC65343 AB089307 BAC55235 AK122658 BAG53647 AK122660 BAG53648 BC033625 AAH33625 BI834364 DQ891340 ABM82266 DQ894522 ABM85448 XM_011510743 XP_011509045 XM_011510744 XP_011509046 NM_001077191 NP_001070659 NM_001077194 NP_001070662 NM_170699 NP_733800
Function	Receptor for bile acid. Bile acid-binding induces its internalization, activation of extracellular signal-regulated kinase and intracellular cAMP production. May be involved in the suppression of macrophage functions by bile acids. {ECO:0000269|PubMed:12419312, ECO:0000269|PubMed:12524422}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:12524422}; Multi-pass membrane protein {ECO:0000269|PubMed:12524422}.
Tissue Specificity	Ubiquitously expressed. Expressed at higher level in spleen and placenta. Expressed at lower level in other tissues. In digestive tissues, it is expressed in stomach, duodenum, ileocecum, ileum, jejunum, ascending colon, transverse colon, descending colon, cecum and liver, but not in esophagus and rectum. {ECO:0000269|PubMed:12044878, ECO:0000269|PubMed:12419312, ECO:0000269|PubMed:12524422}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human GPCR TGR5 full length protein - ab153607 from Abcam Category Protein Source Wheat germ Species Human

GPBAR1 / TGR5 Antibody Blocking Peptide - LS-E28444 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

GPBAR1 / TGR5 Antibody Blocking Peptide - LS-E28443 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

GPBAR1 / TGR5 Antibody Blocking Peptide - LS-E28445 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

GPBAR1 / TGR5 Antibody Blocking Peptide - LS-E28446 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

GPBAR1 / TGR5 Antibody Blocking Peptide - LS-E23399 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human TGR5/GPBAR1 Protein - H00151306-P01 from Novus Biologicals Category Protein Prices $250.00 Sizes 2 µg Source Wheat Germ Species Human

GPCR19 Blocking Peptide - abx161119 from Abbexa Category Peptide Species Human, Mouse, Rat

GPBAR1 fusion protein - ag12749 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

GPCR19 Blocking Peptide - CBP3618 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat

GPBAR1 fusion protein - Ag24893 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET30a Species Human

TGR5/GPBAR1 Recombinant Protein Antigen - NBP2-49376PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

GPBAR1 Peptide, Human - M34GP06480H from Creative Peptides Category Peptide Source Synthetic. Species Human

G-protein coupled bile acid receptor 1 (GPBAR1), Recombinant Protein - MBS7015990 from MyBioSource Category Protein Prices $1,140.00, $2,125.00, $3,335.00 Sizes 10 µg, 50 µg, 100 µg Source Cell Free Expression Species Human

GPCR19 peptide - orb234493 from Biorbyt Category Peptide

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