GPBAR1

Gene Symbol GPBAR1
Entrez Gene 151306
Alt Symbol BG37, GPCR19, GPR131, M-BAR, TGR5
Species Human
Gene Type protein-coding
Description G protein-coupled bile acid receptor 1
Other Description G-protein coupled bile acid receptor 1|G-protein coupled bile acid receptor BG37|G-protein coupled receptor GPCR19|hBG37|hGPCR19|membrane bile acid receptor|membrane-type receptor for bile acids
Swissprots B3KV35 Q8TDU6
Accessions BAB89314 CAD37291 CAD69712 EAW70598 Q8TDU6 AB086170 BAC65343 AB089307 BAC55235 AK122658 BAG53647 AK122660 BAG53648 BC033625 AAH33625 BI834364 DQ891340 ABM82266 DQ894522 ABM85448 XM_011510743 XP_011509045 XM_011510744 XP_011509046 NM_001077191 NP_001070659 NM_001077194 NP_001070662 NM_170699 NP_733800
Function Receptor for bile acid. Bile acid-binding induces its internalization, activation of extracellular signal-regulated kinase and intracellular cAMP production. May be involved in the suppression of macrophage functions by bile acids. {ECO:0000269|PubMed:12419312, ECO:0000269|PubMed:12524422}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:12524422}; Multi-pass membrane protein {ECO:0000269|PubMed:12524422}.
Tissue Specificity Ubiquitously expressed. Expressed at higher level in spleen and placenta. Expressed at lower level in other tissues. In digestive tissues, it is expressed in stomach, duodenum, ileocecum, ileum, jejunum, ascending colon, transverse colon, descending colon, cecum and liver, but not in esophagus and rectum. {ECO:0000269|PubMed:12044878, ECO:0000269|PubMed:12419312, ECO:0000269|PubMed:12524422}.

TGR5 CRISPR/Cas9 KO Plasmid (h) - sc-401875 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TGR5 HDR Plasmid (h) - sc-401875-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TGR5 Double Nickase Plasmid (h) - sc-401875-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TGR5 Double Nickase Plasmid (h2) - sc-401875-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TGR5 CRISPR Activation Plasmid (h) - sc-401875-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TGR5 CRISPR Activation Plasmid (h2) - sc-401875-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TGR5 Lentiviral Activation Particles (h) - sc-401875-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TGR5 Lentiviral Activation Particles (h2) - sc-401875-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TGR5 siRNA (h) - sc-61678 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TGR5 shRNA Plasmid (h) - sc-61678-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TGR5 shRNA (h) Lentiviral Particles - sc-61678-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TGR5/GPBAR1 RNAi - H00151306-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU161041 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN9510 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9510 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

GPBAR1 siRNA (Human) - CRJ5695 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GPBAR1 - MBS828869 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TGR5 CRISPR/Cas9 KO Plasmid (h2) - sc-401875-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TGR5 HDR Plasmid (h2) - sc-401875-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

shRNA set against Human GPBAR1 (NM_170699.2) - SHH305702 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human GPBAR1(NM_001077191.1) - SHH095681 from Creative biogene

Category siRNA
Species Reactivities Human

GPBAR1 shRNA Plasmid (Human) - CHJ5695 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

GPBAR1 miRNA 3'UTR clone - MiUTR1H-04159 from Creative biogene

Species Reactivities Human
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