RAB1B

Gene Symbol	RAB1B
Entrez Gene	81876
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	RAB1B, member RAS oncogene family
Other Description	ras-related protein Rab-1B|small GTP-binding protein
Swissprots	Q9H0U4 A8K7S1
Accessions	Q9H0U4 AF092437 AAP97212 AJ245875 CAC21570 AK292086 BAF84775 AK315333 BAG37733 AL136635 CAB66570 AM393195 CAL38073 BC028331 BC071169 AAH71169 BG717501 CR533462 CAG38493 U66621 AAC51196 NM_030981 NP_112243
Function	The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB1B regulates vesicular transport between the endoplasmic reticulum and successive Golgi compartments. Plays a role in the initial events of the autophagic vacuole development which take place at specialized regions of the endoplasmic reticulum. {ECO:0000269|PubMed:20545908, ECO:0000269|PubMed:9437002}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:11389151}. Membrane {ECO:0000269|PubMed:11389151}; Lipid-anchor {ECO:0000269|PubMed:11389151}; Cytoplasmic side {ECO:0000269|PubMed:11389151}. Preautophagosomal structure membrane {ECO:0000269|PubMed:20545908}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Note=Targeted by REP1 to membranes of specific subcellular compartments including endoplasmic reticulum, Golgi apparatus, and intermediate vesicles between these two compartments. In the GDP-form, colocalizes with GDI in the cytoplasm (By similarity). {ECO:0000250}.
Top Pathways	Legionellosis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

RAB1B-Over-expression-Lysate - LY15946a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

RAB1B overexpression lysate - LY410580 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

RAB1B 293 Cell Lysate - 405396 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

RAB1B Overexpression Lysate (Native) - NBP2-06142 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

Rab 1B (h): 293T Lysate - sc-117417 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

RAB1B Over-expression Lysate Product - GWB-736F0E from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

Human RAB1B HEK293 Cell Lysate (WB positive control) - 15447-H01HL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Human RAB1B Human Cells Transfected Lysate (positive control) (denatured) - orb233023 from Biorbyt Category Cell Lysate Prices $604.00 Sizes 300 μg Species Human

Panoply™ Human RAB1B Knockdown Stable Cell Line - CSC-DC012829 from Creative biogene Category Cell Line Species Human

Human RAB1B Knockout Cell Line-HeLa - CSC-RT0868 from Creative biogene Category Cell Line Species Human

RAB1B KO Cell Lysate-HeLa - CLKO-0369 from Creative biogene Category Cell Lysate

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