CLCN5

Gene Symbol	CLCN5
Entrez Gene	1184
Alt Symbol	CLC5, CLCK2, ClC-5, DENTS, NPHL1, NPHL2, XLRH, XRN, hCIC-K2
Species	Human
Gene Type	protein-coding
Description	chloride channel, voltage-sensitive 5
Other Description	H(+)/Cl(-) exchange transporter 5|chloride transporter ClC-5|voltage-gated chloride ion channel CLCN5
Swissprots	Q5JQD5 B3KPN6 P51795 A1L475 Q7RTN8
Accessions	EAW89929 P51795 AA743724 AK021494 AK025562 AK056560 BAG51748 AK092049 BAG52474 AK290940 BAF83629 AK308089 BC051691 BC130429 AAI30430 BC130431 AAI30432 BF513571 BK000969 DAA01544 BX950885 DA652242 DA737534 HQ258649 ADR83400 X81836 CAA57430 X91906 CAA63000 XM_011543888 XP_011542190 XM_011543889 XP_011542191 NM_000084 NP_000075 NM_001127898 NP_001121370 NM_001127899 NP_001121371 NM_001272102 NP_001259031 NM_001282163 NP_001269092
Function	Proton-coupled chloride transporter. Functions as antiport system and exchanges chloride ions against protons. Important for normal acidification of the endosome lumen. May play an important role in renal tubular function.
Subcellular Location	Golgi apparatus membrane {ECO:0000269|PubMed:19019917}; Multi-pass membrane protein {ECO:0000269|PubMed:19019917}. Endosome membrane {ECO:0000269|PubMed:19019917}; Multi-pass membrane protein {ECO:0000269|PubMed:19019917}. Cell membrane {ECO:0000269|PubMed:19019917}; Multi-pass membrane protein {ECO:0000269|PubMed:19019917}.
Tissue Specificity	Kidney. Moderately expressed in aortic vascular smooth muscle and endothelial cells, and at a slightly higher level in the coronary vascular smooth muscle. {ECO:0000269|PubMed:10198195}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Chloride Channel 5 full length protein - ab158134 from Abcam Category Protein Source Wheat germ Species Human

Human Chloride Channel 5 protein fragment - ab158135 from Abcam Category Protein Source Wheat germ Species Human

ClC-5 / CLCN5 Antibody Blocking Peptide - LS-E12437 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CLCN5 Partial Recombinant Protein - H00001184-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human CLCN5 Protein - H00001184-P01 from Novus Biologicals Category Protein Prices $250.00 Sizes 2 µg Source Wheat Germ Species Human

Clcn5 Blocking Peptide - 33R-5549 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

CLCN5 - H00001184-P01 from Acris Antibodies Category Protein Prices $340.00 Sizes 2 µg Species Human

CLCN5 - H00001184-P01-10 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Species Human

CLCN5 - H00001184-P01-25 from Acris Antibodies Category Protein Prices $520.00 Sizes 25 µg Species Human

CLCN5 - H00001184-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

CLCN5 - H00001184-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

CLCN5 fusion protein - Ag25182 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET30a Species Human

CLCN5 Protein - NBP1-84451PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

CLC5-Antibody-C-term-Blocking-Peptide - BP6329g from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

CLCN5-Blocking-Peptide-N-term - BP20002a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

CLCN5 Peptide, Human - M34GP03218H from Creative Peptides Category Peptide Source Synthetic. Species Human

CLCN5 Recombinant Protein Antigen - NBP2-58621PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E. coli Species Human

H (+)/Cl (-) exchange transporter 5 (CLCN5), Recombinant Protein - MBS953613 from MyBioSource Category Protein Prices $1,375.00, $1,835.00 Sizes 1 mg (E-Coli), 1 mg (Yeast) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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