TFF1

Gene Symbol TFF1
Entrez Gene 7031
Alt Symbol BCEI, D21S21, HP1.A, HPS2, pNR-2, pS2
Species Human
Gene Type protein-coding
Description trefoil factor 1
Other Description breast cancer estrogen-inducible protein|breast cancer estrogen-inducible sequence|gastrointestinal trefoil protein pS2|polypeptide P1.A|protein pS2
Swissprots P04155
Accessions BAA95532 BAB13729 CAA28695 EAX09569 P04155 BC032811 AAH32811 BQ083523 BU539534 M12075 AAA52402 X00474 CAA25155 X52003 CAA36254 NM_003225 NP_003216
Function Stabilizer of the mucous gel overlying the gastrointestinal mucosa that provides a physical barrier against various noxious agents. May inhibit the growth of calcium oxalate crystals in urine. {ECO:0000269|PubMed:16308573}.
Subcellular Location Secreted {ECO:0000269|PubMed:15924415, ECO:0000269|PubMed:3041593}.
Tissue Specificity Found in stomach, with highest levels in the upper gastric mucosal cells (at protein level). Detected in goblet cells of the small and large intestine and rectum, small submucosal glands in the esophagus, mucous acini of the sublingual gland, submucosal glands of the trachea, and epithelial cells lining the exocrine pancreatic ducts but not in the remainder of the pancreas (at protein level). Scattered expression is detected in the epithelial cells of the gallbladder and submucosal glands of the vagina, and weak expression is observed in the bronchial goblet cells of the pseudostratified epithelia in the respiratory system (at protein level). Detected in urine (at protein level). Strongly expressed in breast cancer but at low levels in normal mammary tissue. It is regulated by estrogen in MCF-7 cells. Strong expression found in normal gastric mucosa and in the regenerative tissues surrounding ulcerous lesions of gastrointestinal tract, but lower expression found in gastric cancer (at p

TFF1/pS2 Antibody - 12419 from Cell Signaling Technology

Prices $239.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from MCF7 cells, untreated (-) or 17β-Estradiol-treated (100 nM, 48 hr; +), using TFF1/pS2 Antibody (upper) or GAPDH (D16H11) XP® Rabbit mAb #5174 (lower).

pS2 (A-8) - sc-390889 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
pS2 (A-8): sc-390889. Western blot analysis of pS2 expression in MCF7 whole cell lysate.

pS2 (A-10) - sc-271464 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
pS2 (A-10): sc-271464. Western blot analysis of pS2 expression in MCF7 whole cell lysate.

pS2 (C-20) - sc-7842 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
pS2 (C-20): sc-7842. Western blot analysis of human recombinant pS2 fusion protein.

pS2 (E-16) - sc-22501 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
pS2 (E-16): sc-22501. Western blot analysis of human recombinant pS2 fusion protein.

pS2 (FL-84) - sc-28925 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
pS2 (FL-84): sc-28925. Western blot analysis of pS2 expression in MCF7 whole cell lysate.

pS2 (P-15) - sc-22502 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
pS2 (P-15): sc-22502. Immunofluorescence staining of methanol-fixed MCF7 cells showing cytoplasmic localization.

Anti-Estrogen Inducible Protein pS2 antibody - ab190942 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded Rat intestine tissue labeling Estrogen Inducible Protein pS2  with ab190942 at 1 µg/ml.

Anti-Estrogen Inducible Protein pS2 antibody - ab150578 from Abcam

Prices $376.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed, paraffin embedded Human colon (goblet cells) tissue labeling Estrogen Inducible Protein pS2 with ab150578 at 5µg/ml.

Anti-Estrogen Inducible Protein pS2 antibody - ab50806 from Abcam

Prices $359.00
Sizes 250 µl
Host Rabbit
Clonality Polyclonal

Anti-Estrogen Inducible Protein pS2 antibody - ab59708 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-Estrogen Inducible Protein pS2 antibody - ab98875 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-Estrogen Inducible Protein pS2 antibody (ab98875) at 1 µg/ml + Human fetal stomach lysate at 10 µg

Anti-Estrogen Inducible Protein pS2 antibody [EPR3972] - ab92377 from Abcam

Prices $398.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR3972
All lanes : Anti-Estrogen Inducible Protein pS2 antibody [EPR3972] (ab92377) at 1/1000 dilutionLane 1 : Human stomach lysateLane 2 : MCF-7 cell lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-Estrogen Inducible Protein pS2 antibody [EPR3972] (Alexa Fluor® 488) - ab200799 from Abcam

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR3972
ab200799 staining Estrogen Inducible Protein pS2 in MCF7 cells. The cells were fixed with 4% formaldehyde (10min), permeabilized with 0.1% Triton X-100 for 5 minutes and then blocked with 1% BSA/10% normal goat serum/0.3M glycine in 0.1% PBS-Tween for 1h. The cells were then incubated overnight at +4°C with ab200799 at 1/200 dilution (shown in green) and ab195889, Mouse monoclonal to alpha Tubulin (Alexa Fluor® 594), at 2µg/ml (shown in red). Nuclear DNA was labelled with DAPI (shown in blue).Image was taken with a confocal microscope (Leica-Microsystems, TCS SP8).

Anti-Estrogen Inducible Protein pS2 antibody [EPR3972] (Alexa Fluor® 647) - ab200800 from Abcam

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR3972
ab200800 staining Estrogen Inducible Protein pS2 in MCF7 cells. The cells were fixed with 4% formaldehyde (10min), permeabilized with 0.1% Triton X-100 for 5 minutes and then blocked with 1% BSA/10% normal goat serum/0.3M glycine in 0.1%PBS-Tween for 1h. The cells were then incubated overnight at +4°C with ab200800 at 1/200 dilution (shown in red) and ab195887, Mouse monoclonal to alpha Tubulin (Alexa Fluor® 488), at 2µg/ml (shown in green). Nuclear DNA was labelled with DAPI (shown in blue).Image was taken with a confocal microscope (Leica-Microsystems, TCS SP8).

Anti-Estrogen Inducible Protein pS2 antibody [EPR3972] (HRP) - ab200801 from Abcam

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR3972
Anti-Estrogen Inducible Protein pS2 antibody [EPR3972] (HRP) (ab200801) at 1/5000 dilution + MCF7 (Human breast adenocarcinoma cell line) Whole Cell Lysate at 10 µgdeveloped using the ECL techniquePerformed under reducing conditions.

Anti-Estrogen Inducible Protein pS2 antibody [GE1] - ab95066 from Abcam

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone GE1

Anti-Estrogen Inducible Protein pS2 antibody [GE2] - ab80782 from Abcam

Prices $382.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone GE2
Formalin-fixed, paraffin-embedded human breast cancer stained with ab80782 at 1/50 dilution using a peroxidase-conjugate and AEC chromogen. Note cytoplasmic staining of tumor cells.

Anti-Estrogen Inducible Protein pS2 antibody [pS2.1] - ab3079 from Abcam

Prices $370.00
Sizes 500 µl
Host Mouse
Clonality Monoclonal
Clone pS2.1

Anti-Estrogen Inducible Protein pS2 antibody [SPM313], prediluted - ab54331 from Abcam

Prices $378.00
Sizes 7 ml
Host Mouse
Clonality Monoclonal
Clone SPM313
Ab54331 ready to use staining human breast carcinoma tissue; formalin fixed, paraffin embedded.

Anti-TFF1 / pS2 Antibody (aa67-84) - LS-C312841 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
TFF1 / PS2 antibody. IHC(P): Human Gastric Cancer Tissue.

Anti-TFF1 / pS2 Antibody (aa1-84, Biotin) - LS-C298968 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant TFF1 / PS2.

Anti-TFF1 / pS2 Antibody (Biotin) - LS-C343489 from LifeSpan Bioscience

Prices $305.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-TFF1 / pS2 Antibody - LS-C343518 from LifeSpan Bioscience

Prices $275.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-TFF1 / pS2 Antibody - LS-C335183 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of MCF-7 cell line, using TFF1 antibody.
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