TFF1

Gene Symbol	TFF1
Entrez Gene	7031
Alt Symbol	BCEI, D21S21, HP1.A, HPS2, pNR-2, pS2
Species	Human
Gene Type	protein-coding
Description	trefoil factor 1
Other Description	breast cancer estrogen-inducible protein|breast cancer estrogen-inducible sequence|gastrointestinal trefoil protein pS2|polypeptide P1.A|protein pS2
Swissprots	P04155
Accessions	BAA95532 BAB13729 CAA28695 EAX09569 P04155 BC032811 AAH32811 BQ083523 BU539534 M12075 AAA52402 X00474 CAA25155 X52003 CAA36254 NM_003225 NP_003216
Function	Stabilizer of the mucous gel overlying the gastrointestinal mucosa that provides a physical barrier against various noxious agents. May inhibit the growth of calcium oxalate crystals in urine. {ECO:0000269|PubMed:16308573}.
Subcellular Location	Secreted {ECO:0000269|PubMed:15924415, ECO:0000269|PubMed:3041593}.
Tissue Specificity	Found in stomach, with highest levels in the upper gastric mucosal cells (at protein level). Detected in goblet cells of the small and large intestine and rectum, small submucosal glands in the esophagus, mucous acini of the sublingual gland, submucosal glands of the trachea, and epithelial cells lining the exocrine pancreatic ducts but not in the remainder of the pancreas (at protein level). Scattered expression is detected in the epithelial cells of the gallbladder and submucosal glands of the vagina, and weak expression is observed in the bronchial goblet cells of the pseudostratified epithelia in the respiratory system (at protein level). Detected in urine (at protein level). Strongly expressed in breast cancer but at low levels in normal mammary tissue. It is regulated by estrogen in MCF-7 cells. Strong expression found in normal gastric mucosa and in the regenerative tissues surrounding ulcerous lesions of gastrointestinal tract, but lower expression found in gastric cancer (at p

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human Estrogen Inducible Protein pS2 full length protein - ab201359 from Abcam Category Protein Prices $101.00 Sizes 5 µg Source E. coli Species Human

Human Estrogen Inducible Protein pS2 full length protein - ab89485 from Abcam Category Protein Source E. coli Species Human

Human Estrogen Inducible Protein pS2 full length protein - ab109944 from Abcam Category Protein Source E. coli Species Human

Human Estrogen Inducible Protein pS2 full length protein - ab51744 from Abcam Category Protein Source E. coli Species Human

Recombinant Human TFF1/pS2 Protein - NBP2-35042 from Novus Biologicals Category Protein Prices $69.00, $169.00, $2,669.00 Sizes 5 µg, 20 µg, 1 mg Source E. coli Species Human

Recombinant Human TFF1/pS2 Protein - H00007031-P01 from Novus Biologicals Category Protein Prices $529.00 Sizes 25 µg Source Wheat Germ Species Human

TFF1/pS2 Recombinant Protein - P4157 from Novus Biologicals Category Protein Prices $549.00 Sizes 20 µg Species Human

Recombinant Human TFF1/pS2 Protein - NBP1-99391 from Novus Biologicals Category Protein Prices $190.00 Sizes 20 µg Source E. coli Species Human

pS2/Trefoil Factor 1 Protein - NBP1-99726 from Novus Biologicals Category Protein Species Human

Recombinant Human TFF1/pS2 Protein - NBP1-72375 from Novus Biologicals Category Protein Prices $349.00, $969.00 Sizes 50 µg, 250 µg Source E. coli Species Human

TFF1/pS2 Blocking Peptide - NBP2-13163PEP from Novus Biologicals Category Peptide Prices $329.00 Sizes 100 µg

TFF1 recombinant protein - GTX65262 from GeneTex Category Protein Prices $249.00 Sizes 20 μg Source E. coli Species Human

TFF1 Protein - GTX121461-pro from GeneTex Category Protein Prices $299.00 Sizes 25 μg Source E. coli Species Human

TFF1 Recombinant Protein (Active) - GTX48354-PRO from GeneTex Category Protein Prices $299.00 Sizes 20 μg Source E. coli Species Human

TFF1 Protein (OPPA01660) - OPPA01660 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 5 µg Source E. Coli

TFF1 Protein (OPPA01661) - OPPA01661 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 5 µg Source E. Coli

Human TFF1 protein - orb169416 from Biorbyt Category Protein Prices $187.00, $323.00, $3,128.00 Sizes 5 μg, 20 μg, 1 mg Species Human

Human Trefoil Factor-1 protein - orb80104 from Biorbyt Category Protein Prices $221.00, $357.00, $553.00, $910.00 Sizes 5 μg, 20 μg, 100 μg, 250 μg Source E.coli

Human TFF1 protein - orb244579 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

Human TFF1 protein - orb246010 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

Human TFF1 protein - orb78549 from Biorbyt Category Protein Prices $306.00, $493.00, $638.00 Sizes 10 μg, 50 μg, 100 μg Species Human

Human TFF1 protein (His Tag) - orb80605 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Species Human

TFF1 Blocking Peptide - 33R-7321 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

TFF1 protein (His tag) - 80R-1885 from Fitzgerald Category Protein Prices $340.00 Sizes 50 µg Source E.coli

TIFF1 protein - 30R-AT077 from Fitzgerald Category Protein Prices $225.00 Sizes 20 µg Source E.coli

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