SMYD3

Gene Symbol	SMYD3
Entrez Gene	64754
Alt Symbol	KMT3E, ZMYND1, ZNFN3A1, bA74P14.1
Species	Human
Gene Type	protein-coding
Description	SET and MYND domain containing 3
Other Description	SET and MYND domain-containing protein 3|bA74P14.1 (novel protein)|histone-lysine N-methyltransferase SMYD3|zinc finger MYND domain-containing protein 1|zinc finger protein, subfamily 3A (MYND domain containing), 1|zinc finger, MYND domain containing 1
Swissprots	Q96AI5 B1AN38 Q86TL8 Q9H7B4 A8K0P0 Q8N5Z6
Accessions	CAE91805 CCO13822 EAW77139 EAW77140 EAW77141 EAW77142 EAW77143 EAW77144 Q9H7B4 AB057595 BAB86333 AK023594 BAG51208 AK024733 BAB14981 AK289605 BAF82294 AW173130 AY186742 AAO31695 BC017079 AAH17079 BC031010 AAH31010 BC107725 AAI07726 BI916760 BP231249 DQ581453 DQ892580 ABM83506 DQ895797 ABM86723 XM_011544253 XP_011542555 XM_011544254 XP_011542556 XM_011544255 XP_011542557 XM_011544256 XP_011542558 XM_011544257 XP_011542559 XM_011544258 XP_011542560 XM_011544259 XP_011542561 XM_011544260 XP_011542562 XM_011544261 XP_011542563 XR_949153 NM_001167740 NP_001161212 NM_022743 NP_073580
Function	Histone methyltransferase. Specifically methylates 'Lys- 4' and 'Lys-5' of histone H3, inducing di- and tri-methylation, but not monomethylation. Plays an important role in transcriptional activation as a member of an RNA polymerase complex. Binds DNA containing 5'-CCCTCC-3' or 5'-GAGGGG-3' sequences. {ECO:0000269|PubMed:15235609, ECO:0000269|PubMed:22419068}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:15235609}. Nucleus {ECO:0000269|PubMed:15235609}. Note=Mainly cytoplasmic when cells are arrested at G0/G1. Accumulates in the nucleus at S phase and G2/M.
Tissue Specificity	Expressed in skeletal muscles and testis. Overexpressed in a majority of colorectal and hepatocellular carcinomas. {ECO:0000269|PubMed:15235609}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

SMYD3 overexpression lysate - LY402935 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

SMYD3 293 Cell Lysate - 402556 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

SMYD3 Overexpression Lysate (Native) - NBL1-16262 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

SMYD3 (h2): 293T Lysate - sc-173215 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

SMYD3 Over-expression Lysate Product - GWB-4BC9A0 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

Human SMYD3 / ZMYND1 HEK293 Cell Lysate (WB positive control) - 11230-H18HL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Human SMYD3 / ZMYND1 Insect Cell Lysate (WB positive control) - 11217-H09BL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Human SMYD3 Baculovirus-Insect Cells Transfected Lysate (positive control) (denatured) - orb174935 from Biorbyt Category Cell Lysate Prices $604.00 Sizes 300 μg Species Human

Human SMYD3 Human Cells Transfected Lysate (positive control) (denatured) - orb173320 from Biorbyt Category Cell Lysate Prices $604.00 Sizes 300 μg Species Human

Panoply™ Human SMYD3 Knockdown Stable Cell Line - CSC-DC014787 from Creative biogene Category Cell Line Species Human

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