SMYD3

Gene Symbol SMYD3
Entrez Gene 64754
Alt Symbol KMT3E, ZMYND1, ZNFN3A1, bA74P14.1
Species Human
Gene Type protein-coding
Description SET and MYND domain containing 3
Other Description SET and MYND domain-containing protein 3|bA74P14.1 (novel protein)|histone-lysine N-methyltransferase SMYD3|zinc finger MYND domain-containing protein 1|zinc finger protein, subfamily 3A (MYND domain containing), 1|zinc finger, MYND domain containing 1
Swissprots Q96AI5 B1AN38 Q86TL8 Q9H7B4 A8K0P0 Q8N5Z6
Accessions CAE91805 CCO13822 EAW77139 EAW77140 EAW77141 EAW77142 EAW77143 EAW77144 Q9H7B4 AB057595 BAB86333 AK023594 BAG51208 AK024733 BAB14981 AK289605 BAF82294 AW173130 AY186742 AAO31695 BC017079 AAH17079 BC031010 AAH31010 BC107725 AAI07726 BI916760 BP231249 DQ581453 DQ892580 ABM83506 DQ895797 ABM86723 XM_011544253 XP_011542555 XM_011544254 XP_011542556 XM_011544255 XP_011542557 XM_011544256 XP_011542558 XM_011544257 XP_011542559 XM_011544258 XP_011542560 XM_011544259 XP_011542561 XM_011544260 XP_011542562 XM_011544261 XP_011542563 XR_949153 NM_001167740 NP_001161212 NM_022743 NP_073580
Function Histone methyltransferase. Specifically methylates 'Lys- 4' and 'Lys-5' of histone H3, inducing di- and tri-methylation, but not monomethylation. Plays an important role in transcriptional activation as a member of an RNA polymerase complex. Binds DNA containing 5'-CCCTCC-3' or 5'-GAGGGG-3' sequences. {ECO:0000269|PubMed:15235609, ECO:0000269|PubMed:22419068}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:15235609}. Nucleus {ECO:0000269|PubMed:15235609}. Note=Mainly cytoplasmic when cells are arrested at G0/G1. Accumulates in the nucleus at S phase and G2/M.
Tissue Specificity Expressed in skeletal muscles and testis. Overexpressed in a majority of colorectal and hepatocellular carcinomas. {ECO:0000269|PubMed:15235609}.

SMYD3 (D2Q4V) Rabbit mAb - 12859 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D2Q4V
Western blot analysis of extracts from various cell lines using SMYD3 (D2Q4V) Rabbit mAb.

SMYD3 (C-3) - sc-398085 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
SMYD3 (C-3): sc-398085. Western blot analysis of SMYD3 expression in non-transfected: sc-117752 (A) and human SMYD3 transfected: sc-173215 (B) 293T whole cell lysates.

SMYD3 (C-19) - sc-49517 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

SMYD3 (F-19) - sc-49519 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
SMYD3 (F-19): sc-49519. Western blot analysis of SMYD3 expression in non-transfected: sc-117752 (A) and human SMYD3 transfected: sc-173215 (B) 293T whole cell lysates.

SMYD3 (H-180) - sc-67210 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
SMYD3 (H-180): sc-67210. Western blot analysis of SMYD3 expression in HeLa whole cell lysate.

Anti-SMYD3 antibody - ab155018 from Abcam

Prices $384.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-SMYD3 antibody (ab155018) at 1/1000 dilution + 293T whole cell lysate at 30 µg

Anti-SMYD3 antibody - ab127689 from Abcam

Prices $376.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-SMYD3 antibody (ab127689) at 1/5000 dilution + A549 whole cell lysate at 30 µg

Anti-SMYD3 antibody - ab135076 from Abcam

Host Rabbit
Clonality Polyclonal
Anti-SMYD3 antibody (ab135076) at 1/1000 dilution + 293T whole cell lysate

Anti-SMYD3 antibody [EPR11106(2)] - N-terminal - ab183498 from Abcam

Prices $384.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR11106(2)
All lanes : Anti-SMYD3 antibody [EPR11106(2)] - N-terminal (ab183498) at 1/10000 dilutionLane 1 : HeLa lysateLane 2 : 293 lysateLane 3 : T47-D lysateLysates/proteins at 20 µg per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Anti-SMYD3 antibody [EPR11107(2)] - ab187149 from Abcam

Prices $387.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR11107(2)
All lanes : Anti-SMYD3 antibody [EPR11107(2)] (ab187149) at 1/20000 dilutionLane 1 : MCF-7 cell lysateLane 2 : HeLa cell lysateLane 3 : 293 cell lysateLane 4 : T47-D cell lysateLysates/proteins at 20 µg per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Anti-SMYD3 antibody [GT1088] - ab177163 from Abcam

Prices $376.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone GT1088
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of Human gastric carcinoma labelling SMYD3 with ab177163 at 1:200.

Anti-SMYD3 antibody - ChIP Grade - ab16027 from Abcam

Host Rabbit
Clonality Polyclonal
All lanes : Anti-SMYD3 antibody - ChIP Grade (ab16027) at 1 µgLane 1 : SW480 (Human colon adenocarcinoma cell line) Whole Cell LysateLane 2 : HepG2 (Human hepatocellular liver carcinoma cell line) Whole Cell LysateLane 3 : SW480 (Human colon adenocarcinoma cell line) Whole Cell Lysate with Human SMYD3 peptide (ab16134) at 1 µg/mlLane 4 : HepG2 (Human hepatocellular liver carcinoma cell line) Whole Cell Lysate with Human SMYD3 peptide (ab16134) at 1 µg/mlLysates/proteins at 20 µg per lane.SecondaryGoat Anti-Rabbit IgG H&L (HRP) (ab97051) at 1/10000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-SMYD3 antibody - ChIP Grade - ab85277 from Abcam

Prices $384.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Quiescent human colon carcinoma HCT116 cultures were treated with 10% FBS for three time points (0, 15, 30 minutes) or (0, 30, 60 minutes) were used in Matrix-ChIP and real-time PCR assays at EGR1 gene (Exon1) and 15kb upstream site.

Anti-SMYD3 antibody - N-terminal - ab135650 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-SMYD3 antibody - N-terminal (ab135650) at 1/50 dilution + CEM cell lysate at 35 µg

Anti-SMYD3 Antibody - LS-C332068 from LifeSpan Bioscience

Prices $305.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-SMYD3 Antibody (aa36-85) - LS-C102367 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
SMYD3 antibody LS-C102367 Western blot of Fetal Stomach lysate.

Anti-SMYD3 Antibody (C-Terminus) - LS-C81593 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
MCF7 cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-SMYD3 Antibody - LS-C346352 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence blot of MCF7 cell using SMYD3 antibody. Blue: DAPI for nuclear staining.

Anti-SMYD3 Antibody - LS-C155678 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded Colon ca, using SMYD3 antibody at 1:250 dilution.

Anti-SMYD3 Antibody (aa7-35) - LS-C161332 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
SMYD3 Antibody IHC of formalin-fixed and paraffin-embedded human testis tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

SMYD3 Antibody - NBP1-79393 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SMYD3 Antibody [NBP1-79393] - Quiescent human colon carcinoma cultures were treated with 10% FBS for three time points (0, 15, 30min) or (0, 30, 60min) were used in Matrix-ChIP and real-time PCR assays at EGR1 gene (Exon1) and 15kb upstream site.

SMYD3 Antibody - NBP1-79394 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SMYD3 Antibody [NBP1-79394] - MCF-7 whole cell lysates, concentration 0.2-1 ug/ml.

SMYD3 Antibody - NBP2-20432 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SMYD3 Antibody [NBP2-20432] - IP Sample: 293T whole cell lysate/extract A : Control with 2.5 ug of pre-immune rabbit IgG B : Immunoprecipitation of SMYD3 by 2.5 ug of SMYD3 antibody 10% SDS-PAGE The immunoprecipitated SMYD3 protein was detected by SMYD3 antibody diluted at 1:1000. EasyBlot anti-rabbit IgG (HRP) was used as a secondary reagent.

SMYD3 Antibody - NBP2-20431 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SMYD3 Antibody [NBP2-20431] - Sample (30 ug of whole cell lysate) A: A549 10% SDS PAGE gel, diluted at 1:5000.

SMYD3 Antibody - H00064754-B01-50ul from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
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