SMYD3

Gene Symbol SMYD3
Entrez Gene 64754
Alt Symbol KMT3E, ZMYND1, ZNFN3A1, bA74P14.1
Species Human
Gene Type protein-coding
Description SET and MYND domain containing 3
Other Description SET and MYND domain-containing protein 3|bA74P14.1 (novel protein)|histone-lysine N-methyltransferase SMYD3|zinc finger MYND domain-containing protein 1|zinc finger protein, subfamily 3A (MYND domain containing), 1|zinc finger, MYND domain containing 1
Swissprots Q96AI5 B1AN38 Q86TL8 Q9H7B4 A8K0P0 Q8N5Z6
Accessions CAE91805 CCO13822 EAW77139 EAW77140 EAW77141 EAW77142 EAW77143 EAW77144 Q9H7B4 AB057595 BAB86333 AK023594 BAG51208 AK024733 BAB14981 AK289605 BAF82294 AW173130 AY186742 AAO31695 BC017079 AAH17079 BC031010 AAH31010 BC107725 AAI07726 BI916760 BP231249 DQ581453 DQ892580 ABM83506 DQ895797 ABM86723 XM_011544253 XP_011542555 XM_011544254 XP_011542556 XM_011544255 XP_011542557 XM_011544256 XP_011542558 XM_011544257 XP_011542559 XM_011544258 XP_011542560 XM_011544259 XP_011542561 XM_011544260 XP_011542562 XM_011544261 XP_011542563 XR_949153 NM_001167740 NP_001161212 NM_022743 NP_073580
Function Histone methyltransferase. Specifically methylates 'Lys- 4' and 'Lys-5' of histone H3, inducing di- and tri-methylation, but not monomethylation. Plays an important role in transcriptional activation as a member of an RNA polymerase complex. Binds DNA containing 5'-CCCTCC-3' or 5'-GAGGGG-3' sequences. {ECO:0000269|PubMed:15235609, ECO:0000269|PubMed:22419068}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:15235609}. Nucleus {ECO:0000269|PubMed:15235609}. Note=Mainly cytoplasmic when cells are arrested at G0/G1. Accumulates in the nucleus at S phase and G2/M.
Tissue Specificity Expressed in skeletal muscles and testis. Overexpressed in a majority of colorectal and hepatocellular carcinomas. {ECO:0000269|PubMed:15235609}.

SMYD3 CRISPR/Cas9 KO Plasmid (h) - sc-402128 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SMYD3 HDR Plasmid (h) - sc-402128-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SMYD3 Double Nickase Plasmid (h) - sc-402128-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SMYD3 Double Nickase Plasmid (h2) - sc-402128-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SMYD3 CRISPR Activation Plasmid (h) - sc-402128-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SMYD3 CRISPR Activation Plasmid (h2) - sc-402128-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SMYD3 Lentiviral Activation Particles (h) - sc-402128-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SMYD3 Lentiviral Activation Particles (h2) - sc-402128-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SMYD3 siRNA (h) - sc-61575 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SMYD3 shRNA Plasmid (h) - sc-61575-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SMYD3 shRNA (h) Lentiviral Particles - sc-61575-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU044291 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN19817 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19817 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR01415 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr01415

SMYD3 siRNA (Human) - CRJ2064 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SMYD3 RNAi - H00064754-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

SMYD3 - MBS8218231 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human SMYD3 (NM_022743.2) - SHH413788 from Creative biogene

Category siRNA
Species Reactivities Human

Human SMYD3 siRNA - orb272565 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SMYD3 shRNA Plasmid (Human) - CHJ2064 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SMYD3 miRNA 3'UTR clone - MiUTR3H-10224 from Creative biogene

Species Reactivities Human
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