SMYD3

Gene Symbol	SMYD3
Entrez Gene	64754
Alt Symbol	KMT3E, ZMYND1, ZNFN3A1, bA74P14.1
Species	Human
Gene Type	protein-coding
Description	SET and MYND domain containing 3
Other Description	SET and MYND domain-containing protein 3|bA74P14.1 (novel protein)|histone-lysine N-methyltransferase SMYD3|zinc finger MYND domain-containing protein 1|zinc finger protein, subfamily 3A (MYND domain containing), 1|zinc finger, MYND domain containing 1
Swissprots	Q96AI5 B1AN38 Q86TL8 Q9H7B4 A8K0P0 Q8N5Z6
Accessions	CAE91805 CCO13822 EAW77139 EAW77140 EAW77141 EAW77142 EAW77143 EAW77144 Q9H7B4 AB057595 BAB86333 AK023594 BAG51208 AK024733 BAB14981 AK289605 BAF82294 AW173130 AY186742 AAO31695 BC017079 AAH17079 BC031010 AAH31010 BC107725 AAI07726 BI916760 BP231249 DQ581453 DQ892580 ABM83506 DQ895797 ABM86723 XM_011544253 XP_011542555 XM_011544254 XP_011542556 XM_011544255 XP_011542557 XM_011544256 XP_011542558 XM_011544257 XP_011542559 XM_011544258 XP_011542560 XM_011544259 XP_011542561 XM_011544260 XP_011542562 XM_011544261 XP_011542563 XR_949153 NM_001167740 NP_001161212 NM_022743 NP_073580
Function	Histone methyltransferase. Specifically methylates 'Lys- 4' and 'Lys-5' of histone H3, inducing di- and tri-methylation, but not monomethylation. Plays an important role in transcriptional activation as a member of an RNA polymerase complex. Binds DNA containing 5'-CCCTCC-3' or 5'-GAGGGG-3' sequences. {ECO:0000269|PubMed:15235609, ECO:0000269|PubMed:22419068}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:15235609}. Nucleus {ECO:0000269|PubMed:15235609}. Note=Mainly cytoplasmic when cells are arrested at G0/G1. Accumulates in the nucleus at S phase and G2/M.
Tissue Specificity	Expressed in skeletal muscles and testis. Overexpressed in a majority of colorectal and hepatocellular carcinomas. {ECO:0000269|PubMed:15235609}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human SMYD3 full length protein - ab125590 from Abcam Category Protein Source Baculovirus infected sf9 cells Species Human

Human SMYD3 full length protein - ab153490 from Abcam Category Protein Source Wheat germ Species Human

Human SMYD3 full length protein - ab196410 from Abcam Category Protein Source Baculovirus infected sf9 cells Species Human

Human SMYD3 peptide - ab16134 from Abcam Category Peptide

Human SMYD3 protein fragment - ab153491 from Abcam Category Protein Source Wheat germ Species Human

Human SMYD3 protein fragment - ab80377 from Abcam Category Protein Source Baculovirus infected sf9 cells Species Human

SMYD3 Antibody Blocking Peptide - LS-E18293 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SMYD3 Antibody Blocking Peptide - LS-E18292 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SMYD3 Antibody Blocking Peptide - LS-E8883 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human SMYD3 Protein - H00064754-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human SMYD3 Protein - H00064754-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

SMYD3-Antibody-N-term-Blocking-Peptide - BP7344a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human SET and MYND domain containing 3 protein - orb83552 from Biorbyt Category Protein Prices $323.00, $612.00 Sizes 20 μg, 50 μg Source Human Species Human

Human SET and MYND domain containing 3 protein - orb83495 from Biorbyt Category Protein Prices $323.00, $612.00 Sizes 20 μg, 50 μg Source Insect Species Human

SMYD3 Blocking Peptide - 33R-5022 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

SMYD3 Blocking Peptide - 33R-7347 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

SMYD3 - H00064754-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

SMYD3 - H00064754-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

SMYD3 - H00064754-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

SMYD3 - H00064754-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

SMYD3 fusion protein - ag2624 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant SMYD3 protein - 31407 from ActiveMotif Category Protein Prices $395.00 Sizes 20 μg Source Baculovirus Species Human

Recombinant Human SET And MYND Domain Containing 2, His-tagged - SMYD2-921H from Creative Biomart Category Protein Source Insect cells .

Recombinant Human SET And MYND Domain Containing 3, GST-tagged - SMYD3-1634H from Creative Biomart Category Protein Species Human

Recombinant Human SET And MYND Domain Containing 3, GST-tagged - SMYD3-470H from Creative Biomart Category Protein Source Sf9 .

Search more