GLYAT

Gene Symbol GLYAT
Entrez Gene 10249
Alt Symbol ACGNAT, CAT, GAT
Species Human
Gene Type protein-coding
Description glycine-N-acyltransferase
Other Description AAc|HRP-1(CLP)|acyl-CoA:glycine N-acyltransferase|aralkyl acyl-CoA N-acyltransferase|aralkyl acyl-CoA:amino acid N-acyltransferase|aralkyl-CoA N-acyltransferase|benzoyl-coenzyme A:glycine N-acyltransferase|glycine N-acyltransferase|glycine N-benzoyltransferase
Swissprots Q96QK7 Q6IB77 O14833
Accessions EAW73822 EAW73823 EAW73824 Q6IB77 AB013093 AB665285 BAL43174 AF023466 AAB81453 AI253073 AI793012 AI793201 AW024233 BC009785 AAH09785 BG401676 BG617408 BP277146 CB161978 CR456927 CAG33208 DQ892712 ABM83638 DQ895964 ABM86890 DR004166 NM_005838 NP_005829 NM_201648 NP_964011
Function Mitochondrial acyltransferase which transfers an acyl group to the N-terminus of glycine and glutamine, although much less efficiently. Can conjugate numerous substrates to form a variety of N-acylglycines, with a preference for benzoyl-CoA over phenylacetyl-CoA as acyl donors. Thereby detoxify xenobiotics, such as benzoic acid or salicylic acid, and endogenous organic acids, such as isovaleric acid. {ECO:0000269|PubMed:22475485, ECO:0000269|PubMed:7802672}.
Subcellular Location Mitochondrion {ECO:0000269|PubMed:22475485}.
Tissue Specificity Predominantly expressed in liver (at protein level) and kidney. Down-regulated in hepatocellular carcinoma and other liver cancers. {ECO:0000269|PubMed:22475485}.
Top Pathways Phenylalanine metabolism

GLYAT (N-12) - sc-83833 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
GLYAT (N-12): sc-83833. Western blot analysis of GLYAT expression in Hep G2 (A) and Caki-1 (B) whole cell lysates.

Anti-GLYAT antibody - ab118322 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Anti-GLYAT antibody (ab118322) at 1 µg/ml + Recombinant GLYAT protein (the immunogen) with a proprietary tag at 0.2 µg

Anti-GLYAT antibody - ab171388 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-GLYAT antibody (ab171388) at 1/100 dilution + 293 cell line lysate at 35 µg

Anti-GLYAT antibody - ab197162 from Abcam

Prices $370.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-GLYAT antibody (ab197162) at 1/500 dilutionLane 1 : 293 cell lysateLane 2 : Human fetal liver lysate

Anti-GLYAT Antibody (aa171-199, AP) - LS-C257808 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GLYAT Antibody (aa171-199, Biotin) - LS-C257809 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GLYAT Antibody (aa171-199, APC) - LS-C257810 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GLYAT Antibody (aa171-199, Azide-free, HRP) - LS-C257812 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GLYAT Antibody (aa171-199, FITC) - LS-C257811 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GLYAT Antibody (aa171-199, PE) - LS-C257813 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GLYAT Antibody - LS-C308090 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-GLYAT Antibody (aa170-200) - LS-C321667 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GLYAT Antibody (aa71-120) - LS-C102314 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
GLYAT antibody LS-C102314 Western blot of HepG2 cell lysate.

Anti-GLYAT Antibody (aa171-199) - LS-C166528 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
GLYAT Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human liver tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-GLYAT Antibody (clone 1A10) - LS-C134021 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1A10
Immunoperoxidase of monoclonal antibody to GLYAT on formalin-fixed paraffin-embedded human salivary gland. [antibody concentration 3 ug/ml]

GLYAT Antibody - NBP1-54714 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: GLYAT Antibody [NBP1-54714] - Titration: 0.2-1 ug/ml, Positive Control: HepG2 cell lysate.

GLYAT Antibody (1A10) - H00010249-M07 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1A10

GLYAT Antibody - H00010249-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: GLYAT Antibody [H00010249-B01P] - Analysis of GLYAT expression in transfected 293T cell line by GLYAT polyclonal antibody. Lane 1: GLYAT transfected lysate(17.93 KDa). Lane 2: Non-transfected lysate.

Monoclonal Anti-GLYAT antibody produced in mouse - SAB1402510 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1A10
<B>Immunohistochemistry</B><BR/>Monoclonal Anti-GLYAT, antibody produced in mouse, clone 1A10, purified immunoglobulin: <B>Cat. No. SAB1402510</B>: Antibody concentration: 3 μg/mL using human salivary gland tissue.

Anti-GLYAT antibody produced in mouse - SAB1406959 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-GLYAT: <B>Cat. No. SAB1406959</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~17.9 kDa using GLYAT transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-GLYAT antibody produced in rabbit - SAB2100933 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-GLYAT: <B>Cat. No.SAB2100933</B>: GLYAT in HepG2 cell lysate with GLYAT antibody at 1.0 μg/mL.

GLYAT antibody - N-terminal region (ARP48682_P050) - ARP48682_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

GLYAT-Antibody-Center - AP13064c from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
GLYAT Antibody (Center) (Cat. #AP13064c) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the GLYAT antibody detected the GLYAT protein (arrow).

GLYAT antibody, N-term - GTX46205 from GeneTex

Prices $319.00
Sizes 50 μg
Host Rabbit
Clonality Polyclonal
Anti-GLYAT antibody, N-term used in IHC (Formalin-fixed paraffin-embedded sections). GTX46205

GLYAT Antibody - middle region (OAAB09357) - OAAB09357 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
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