GLYAT

Gene Symbol GLYAT
Entrez Gene 10249
Alt Symbol ACGNAT, CAT, GAT
Species Human
Gene Type protein-coding
Description glycine-N-acyltransferase
Other Description AAc|HRP-1(CLP)|acyl-CoA:glycine N-acyltransferase|aralkyl acyl-CoA N-acyltransferase|aralkyl acyl-CoA:amino acid N-acyltransferase|aralkyl-CoA N-acyltransferase|benzoyl-coenzyme A:glycine N-acyltransferase|glycine N-acyltransferase|glycine N-benzoyltransferase
Swissprots Q96QK7 Q6IB77 O14833
Accessions EAW73822 EAW73823 EAW73824 Q6IB77 AB013093 AB665285 BAL43174 AF023466 AAB81453 AI253073 AI793012 AI793201 AW024233 BC009785 AAH09785 BG401676 BG617408 BP277146 CB161978 CR456927 CAG33208 DQ892712 ABM83638 DQ895964 ABM86890 DR004166 NM_005838 NP_005829 NM_201648 NP_964011
Function Mitochondrial acyltransferase which transfers an acyl group to the N-terminus of glycine and glutamine, although much less efficiently. Can conjugate numerous substrates to form a variety of N-acylglycines, with a preference for benzoyl-CoA over phenylacetyl-CoA as acyl donors. Thereby detoxify xenobiotics, such as benzoic acid or salicylic acid, and endogenous organic acids, such as isovaleric acid. {ECO:0000269|PubMed:22475485, ECO:0000269|PubMed:7802672}.
Subcellular Location Mitochondrion {ECO:0000269|PubMed:22475485}.
Tissue Specificity Predominantly expressed in liver (at protein level) and kidney. Down-regulated in hepatocellular carcinoma and other liver cancers. {ECO:0000269|PubMed:22475485}.
Top Pathways Phenylalanine metabolism

GLYAT - MBS1267457 from MyBioSource

Prices $175.00
Sizes 10ug plasmid + 200ul glycerol stock
Species Human
Accession BC009785

Mouse GLYAT ORF clone (NM_201648.2) - CDCL112199 from Creative biogene

Species Human

Human GLYAT ORF clone (NM_005838.3) - CDCL112201 from Creative biogene

Species Human

Human GLYAT ORF Clone (BC009785) - CDCS412446 from Creative biogene

Species Human
Accession Q6IB77

Human GLYAT ORF clone (BC009785) - CDCB159337 from Creative biogene

Species Human

Human GLYAT Gene cDNA Clone - orb143391 from Biorbyt

Prices $264.00
Sizes 10 μg
Species Human
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