NCKIPSD

Gene Symbol NCKIPSD
Entrez Gene 51517
Alt Symbol AF3P21, DIP, DIP1, ORF1, SPIN90, VIP54, WASLBP, WISH
Species Human
Gene Type protein-coding
Description NCK interacting protein with SH3 domain
Other Description 54 kDa VacA-interacting protein|54 kDa vimentin-interacting protein|90 kDa SH3 protein interacting with Nck|NCK-interacting protein with SH3 domain|SH3 adapter protein SPIN90|SH3 protein interacting with Nck, 90 kDa|WASP-interacting SH3-domain protein|dia interacting protein|dia-interacting protein 1|diaphanous protein interacting protein|wiskott-Aldrich syndrome protein-interacting protein
Swissprots Q8TC10 Q9NZQ3 Q6SPF3 Q9UGM8 Q6GU34 B4DFL5
Accessions BAB63204 BAB63205 EAW64915 EAW64916 EAW64917 EAW64918 Q9NZQ3 AF178432 AAF35985 AF303581 AAK09094 AI863106 AJ242655 CAB65089 AK294151 BAG57476 AY453794 AAR83735 BC006255 BC016052 AAH16052 BC026280 AAH26280 HY010884 HY050918 JF432321 ADZ15538 NM_016453 NP_057537 NM_184231 NP_909119
Function Has an important role in stress fiber formation induced by active diaphanous protein homolog 1 (DRF1). Induces microspike formation, in vivo (By similarity). In vitro, stimulates N-WASP- induced ARP2/3 complex activation in the absence of CDC42 (By similarity). May play an important role in the maintenance of sarcomeres and/or in the assembly of myofibrils into sarcomeres. Implicated in regulation of actin polymerization and cell adhesion. Plays a role in angiogenesis. {ECO:0000250, ECO:0000269|PubMed:22419821}.
Subcellular Location Nucleus. Note=Colocalizes with DRF1 at membrane ruffles, and with Nck at Z-disks in mature cardiac myocytes.
Tissue Specificity Highest expression in heart, brain, skeletal muscle, kidney and liver. Lower levels in placenta, lung, small intestine and leukocytes. Weak expression in colon, thymus and spleen. {ECO:0000269|PubMed:10619843}.

NCK interacting protein with SH3 domain, ELISA Kit - MBS9318675 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human NCKIPSD ELISA Kit - E025887 from Biobool

Category ELISA Kit

Human TSC22 domain family protein 3 (TSC22D3) ELISA Kit - AE13172HU from ARP American Research Products

Category ELISA Kit
Prices $549.00
Sizes 96 t
Sensitivity 7.15 pg/mL
Range 18.52-1500 pg/mL
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