NCKIPSD

Gene Symbol	NCKIPSD
Entrez Gene	51517
Alt Symbol	AF3P21, DIP, DIP1, ORF1, SPIN90, VIP54, WASLBP, WISH
Species	Human
Gene Type	protein-coding
Description	NCK interacting protein with SH3 domain
Other Description	54 kDa VacA-interacting protein|54 kDa vimentin-interacting protein|90 kDa SH3 protein interacting with Nck|NCK-interacting protein with SH3 domain|SH3 adapter protein SPIN90|SH3 protein interacting with Nck, 90 kDa|WASP-interacting SH3-domain protein|dia interacting protein|dia-interacting protein 1|diaphanous protein interacting protein|wiskott-Aldrich syndrome protein-interacting protein
Swissprots	Q8TC10 Q9NZQ3 Q6SPF3 Q9UGM8 Q6GU34 B4DFL5
Accessions	BAB63204 BAB63205 EAW64915 EAW64916 EAW64917 EAW64918 Q9NZQ3 AF178432 AAF35985 AF303581 AAK09094 AI863106 AJ242655 CAB65089 AK294151 BAG57476 AY453794 AAR83735 BC006255 BC016052 AAH16052 BC026280 AAH26280 HY010884 HY050918 JF432321 ADZ15538 NM_016453 NP_057537 NM_184231 NP_909119
Function	Has an important role in stress fiber formation induced by active diaphanous protein homolog 1 (DRF1). Induces microspike formation, in vivo (By similarity). In vitro, stimulates N-WASP- induced ARP2/3 complex activation in the absence of CDC42 (By similarity). May play an important role in the maintenance of sarcomeres and/or in the assembly of myofibrils into sarcomeres. Implicated in regulation of actin polymerization and cell adhesion. Plays a role in angiogenesis. {ECO:0000250, ECO:0000269|PubMed:22419821}.
Subcellular Location	Nucleus. Note=Colocalizes with DRF1 at membrane ruffles, and with Nck at Z-disks in mature cardiac myocytes.
Tissue Specificity	Highest expression in heart, brain, skeletal muscle, kidney and liver. Lower levels in placenta, lung, small intestine and leukocytes. Weak expression in colon, thymus and spleen. {ECO:0000269|PubMed:10619843}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human NCKIPSD full length protein - ab162581 from Abcam Category Protein Source Wheat germ Species Human

Human NCKIPSD protein fragment - ab162582 from Abcam Category Protein Source Wheat germ Species Human

NCKIPSD / AF3P21 Antibody Blocking Peptide - LS-E21771 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NCKIPSD / AF3P21 Antibody Blocking Peptide - LS-E21772 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human NCKIPSD Protein - H00051517-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human NCKIPSD Protein - H00051517-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

SPIN90-Antibody-Center-Blocking-peptide - BP11870c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

SPIN90-Antibody-C-term-Blocking-Peptide - BP4782b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human NCKIPSD protein (GST Tag) - orb139382 from Biorbyt Category Protein Prices $323.00, $646.00 Sizes 20 μg, 100 μg Source E. coli Species Human

Viral ORF1 protein - orb244687 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Virus

NCKIPSD Blocking Peptide - 33R-5542 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

AF3P21 Blocking Peptide - abx161010 from Abbexa Category Peptide Species Human, Mouse, Rat

NCKIPSD - H00051517-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

NCKIPSD - H00051517-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

NCKIPSD - H00051517-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

NCKIPSD - H00051517-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

NCKIPSD fusion protein - Ag1915 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human NCKIPSD, GST tagged - NCKIPSD-514H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human NCKIPSD, GST-tagged - NCKIPSD-1212H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human NCKIPSD, GST-tagged - NCKIPSD-16H from Creative Biomart Category Protein Source E. coli Species Human

Human NCKIPSD / SPIN90 Protein (GST Tag) - 13642-H09E-20 from Sino Biological Category Protein Prices $138.00, $348.00 Sizes 20 µg, 100 µg Source E. coli Species Human

AF3P21 Blocking Peptide - CBP3509 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat

Recombinant Hepatitis E virus genotype 1 Non-structural polyprotein pORF1 (ORF1) ,partial - CSB-YP327230HGE CSB-BP327230HGE CSB-MP327230HGE from Cusabio Category Protein Source Yeast or Baculovirus or Mammalian cell Species Human

Recombinant Hepatitis E virus genotype 1 Non-structural polyprotein pORF1 - CSB-EP327230HGE from Cusabio Category Protein Source E.coli

Recombinant Human NCK-interacting protein with SH3 domain(NCKIPSD) - CSB-YP868371HU CSB-EP868371HU CSB-BP868371HU CSB-MP868371HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Search more