MCM3

Gene Symbol	MCM3
Entrez Gene	4172
Alt Symbol	HCC5, P1-MCM3, P1.h, RLFB
Species	Human
Gene Type	protein-coding
Description	minichromosome maintenance complex component 3
Other Description	DNA polymerase alpha holoenzyme-associated protein P1|DNA replication factor MCM3|DNA replication licensing factor MCM3|MCM3 minichromosome maintenance deficient 3|RLF subunit beta|cervical cancer proto-oncogene 5|hRlf beta subunit|minichromosome maintenance deficient 3|p102|replication licensing factor, beta subunit
Swissprots	B4DWW4 Q9BTR3 P25205 Q9NUE7 Q92660
Accessions	AAT27321 CBX85467 EAX04366 EAX04367 P25205 AI683709 AK222586 BAD96306 AK299566 BAG61508 AK300754 BAG62421 AK301704 BAG63176 AK312928 BAG35772 AY032603 AAK56392 BC001626 AAH01626 BC003509 AAH03509 BI463632 D38073 BAA07267 DC404097 DQ893654 ABM84580 DQ895840 ABM86766 X62153 CAA44078 NM_001270472 NP_001257401 NM_002388 NP_002379
Function	Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for DNA replication and cell proliferation.
Subcellular Location	Nucleus.
Top Pathways	DNA replication, Cell cycle

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Rabbit anti-MCM3 Antibody, Affinity Purified - PLA0061 from Sigma-Aldrich Prices $323.50 Sizes 100 µl

Goat anti-MCM3 Antibody, Affinity Purified - PLA0038 from Sigma-Aldrich Prices $323.50 Sizes 100 µl

minichromosome maintenance complex component 3, ELISA Kit - MBS9319983 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Minichromosome Maintenance Deficient 3 (MCM3), ELISA Kit - MBS2024708 from MyBioSource Category ELISA Kit Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 0.058ng/mL. Range 0.156-10ng/mL

ELISA Kit for Minichromosome Maintenance Deficient 3 (MCM3) - SEE653Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.058ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

ELISA Kit for Minichromosome Maintenance Deficient 3 (MCM3) - SEE653Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.058ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA's were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

Human Minichromosome Maintenance Deficient 3 ELISA Kit - abx156883 from Abbexa Category ELISA Kit Range 0.156 ng/ml - 10 ng/ml

Human MCM3 ELISA Kit (Sandwich ELISA) - LS-F25468 from LifeSpan Bioscience Category ELISA Kit Prices $780.00 Sizes 1 plate Sensitivity 0.058 ng/ml Range 0.156-10 ng/ml

Human Minichromosome Maintenance Deficient 3 (MCM3) ELISA Kit - EKU09202 from Biomatik Category ELISA Kit Prices $735.00, $3,234.00, $5,880.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 0.058 ng/mL Range 0.156-10 ng/mL

Human MCM3 ELISA Kit - E024581 from Biobool Category ELISA Kit Sensitivity Typically less than 0.058ng/mL.

MCM3 ELISA Kit (Human) (OKCD00441) - OKCD00441 from Aviva Systems Biology Category ELISA Kit Prices $545.00 Sizes 96 wells Sensitivity < 0.058 ng/mL Range 0.156-10 ng/mL

Human DNA replication licensing factor MCM3 (MCM3) ELISA Kit - AE34023HU from ARP American Research Products Category ELISA Kit Prices $549.00 Sizes 96 t Sensitivity 0.058 ng/mL Range 0.156-10 ng/mL

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