MCM3

Gene Symbol	MCM3
Entrez Gene	4172
Alt Symbol	HCC5, P1-MCM3, P1.h, RLFB
Species	Human
Gene Type	protein-coding
Description	minichromosome maintenance complex component 3
Other Description	DNA polymerase alpha holoenzyme-associated protein P1|DNA replication factor MCM3|DNA replication licensing factor MCM3|MCM3 minichromosome maintenance deficient 3|RLF subunit beta|cervical cancer proto-oncogene 5|hRlf beta subunit|minichromosome maintenance deficient 3|p102|replication licensing factor, beta subunit
Swissprots	B4DWW4 Q9BTR3 P25205 Q9NUE7 Q92660
Accessions	AAT27321 CBX85467 EAX04366 EAX04367 P25205 AI683709 AK222586 BAD96306 AK299566 BAG61508 AK300754 BAG62421 AK301704 BAG63176 AK312928 BAG35772 AY032603 AAK56392 BC001626 AAH01626 BC003509 AAH03509 BI463632 D38073 BAA07267 DC404097 DQ893654 ABM84580 DQ895840 ABM86766 X62153 CAA44078 NM_001270472 NP_001257401 NM_002388 NP_002379
Function	Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for DNA replication and cell proliferation.
Subcellular Location	Nucleus.
Top Pathways	DNA replication, Cell cycle

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

MCM3 Antibody Blocking Peptide - LS-E2899 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MCM3 Antibody Blocking Peptide - LS-E13136 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MCM3 Antibody Blocking Peptide - LS-E13137 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human MCM3 Protein - H00004172-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

MCM3-Antibody-N-term-Blocking-peptide - BP14026a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

MCM3 Blocking Peptide - 33R-10056 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

MCM3 Blocking Peptide - 33R-8710 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

MCM3 - H00004172-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

MCM3 - H00004172-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

MCM3 fusion protein - Ag7966 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

MCM3 fusion protein - Ag8122 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human MCM3, His-tagged - MCM3-28038TH from Creative Biomart Category Protein Source E. coli

Recombinant Human MCM3, GST-tagged - MCM3-23H from Creative Biomart Category Protein Source Wheat germ Species Human

Recombinant Human DNA replication licensing factor MCM3(MCM3) ,partial - CSB-YP013591HU CSB-EP013591HU CSB-BP013591HU CSB-MP013591HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

MCM3 - TP300208 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

MCM3 Recombinant Protein Antigen - NBP1-85797PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

MCM3 Recombinant Protein Antigen - NBP1-85796PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

MCM3 Blocking Peptide (OESA09457) - OESA09457 from Aviva Systems Biology Category Peptide Prices $255.00 Sizes 50 µg Species Human

MCM3 Peptide, Human - M34GP09314H from Creative Peptides Category Peptide Source Synthetic. Species Human

Recombinant Minichromosome Maintenance Deficient 3 (MCM3) - RPU50689 from Biomatik Category Protein Prices $182.00, $315.00, $482.00, $602.00 Sizes 10 µg, 50 µg, 100 µg, 200 µg Source E.coli Species Human

DNA replication licensing factor MCM3 (MCM3), partial, Recombinant Protein - MBS954208 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Minichromosome Maintenance Deficient 3, Recombinant Protein - MBS2034613 from MyBioSource Category Protein Prices $160.00, $320.00, $495.00 Sizes 10 µg, 50 µg, 100 µg Source E Coli Source: Prokaryotic expression Species Human

Minichromosome Maintenance Deficient 3, Recombinant Protein - MBS2034614 from MyBioSource Category Protein Prices $170.00, $345.00, $535.00 Sizes 10 µg, 50 µg, 100 µg Source E Coli Source: Prokaryotic expression Species Mouse

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