RNF135

Gene Symbol	RNF135
Entrez Gene	84282
Alt Symbol	L13, MMFD, REUL, Riplet
Species	Human
Gene Type	protein-coding
Description	ring finger protein 135
Other Description	E3 ubiquitin-protein ligase RNF135\|RIG-I E3 ubiquitin ligase
Swissprots	F5GX60 A0AVM5 B2R7G9 B6ZLM5 Q9BSE9 Q8IUD6
Accessions	EAW80286 Q8IUD6 AB470605 BAG84604 AI634044 AJ496729 CAD43140 AK122646 BAG53638 AK122709 BAG53681 AK226030 AK312979 BAG35816 AY598332 AAT06743 BC005084 AAH05084 BC082262 BC126420 AAI26421 BC126422 AAI26423 BC144143 DA878616 XM_005258043 XP_005258100 XM_006722138 XP_006722201 NM_001184992 NP_001171921 NM_032322 NP_115698 NM_197939 NP_922921
Function	Acts as an E2-dependent E3 ubiquitin-protein ligase, involved in innate immune defense against viruses. Ubiquitinates DDX58 and is required for full activation of the DDX58 signaling resulting in interferon beta production. {ECO:0000269\|PubMed:19017631, ECO:0000269\|PubMed:19484123}.
Subcellular Location	Cytoplasm {ECO:0000269\|PubMed:19484123}.
Tissue Specificity	Expressed in skeletal muscle, spleen, kidney, placenta, prostate, stomach, thyroid and tongue. Also weakly expressed in heart, thymus, liver and lung. {ECO:0000269\|PubMed:19017631}.

RNF135 (P-13) - sc-132800 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

RNF135 (J-24) - sc-102092 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	50 µg/0.5 ml
Host	Rabbit
Clonality	Polyclonal

RNF135 (J-24): sc-102092. Western blot analysis of RNF135 expression in Jurkat whole cell lysate.

RNF135 (L-14) - sc-132799 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

RNF135 (V-13) - sc-132801 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

Anti-RNF135 antibody - ab28636 from Abcam

Prices	$370.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-RNF135 antibody (ab28636) at 0.5 µg/ml + Jurkat cell lysateSecondaryHRP conjugated anti-Rabbit IgGObserved band size : 48 kDa (why is the actual band size different from the predicted?)

Anti-RNF135 antibody - ab169134 from Abcam

Prices	$370.00
Sizes	50 µl
Host	Mouse
Clonality	Polyclonal

All lanes : Anti-RNF135 antibody (ab169134) at 1/500 dilutionLane 1 : RNF135 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.developed using the ECL technique

Anti-RNF135 antibody - C-terminal - ab174195 from Abcam

Prices	$370.00
Sizes	400 µl
Host	Rabbit
Clonality	Polyclonal

Anti-RNF135 antibody - C-terminal (ab174195) at 1/100 dilution + 293 cell lysate at 35 µg

Anti-RNF135 Antibody (aa375-401, AP) - LS-C268373 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-RNF135 Antibody (aa375-401, APC) - LS-C268374 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-RNF135 Antibody (aa375-401, Biotin) - LS-C268376 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-RNF135 Antibody (aa375-401, FITC) - LS-C268377 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-RNF135 Antibody (aa199-248) - LS-C29864 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Anti-RNF135 Antibody (aa375-401, PE) - LS-C268379 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-RNF135 Antibody (aa375-401, Azide-free, HRP) - LS-C268378 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-RNF135 Antibody (aa374-402) - LS-C324720 from LifeSpan Bioscience

Prices	$345.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-RNF135 Antibody (aa111-160) - LS-C145482 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

RNF135 antibody LS-C145482 Western blot of HepG2 Cell lysate. Antibody concentration 1 ug/ml.

Anti-RNF135 Antibody (aa107-156) - LS-C107493 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

RNF135 antibody LS-C107493 Western blot of COLO205 cell lysate.

Anti-RNF135 Antibody (aa375-401) - LS-C155998 from LifeSpan Bioscience

Prices	$295.00
Sizes	400 µl
Host	Rabbit
Clonality	Polyclonal

RNF135 Antibody western blot of 293 cell line lysates (35 ug/lane). The RNF135 antibody detected the RNF135 protein (arrow).

RNF135 Antibody - NBP1-81212 from Novus Biologicals

Prices	$419.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Western Blot: RNF135 Antibody [NBP1-81212] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-479

RNF135 Antibody - H00084282-D01P from Novus Biologicals

Prices	$399.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Western Blot: RNF135 Antibody [H00084282-D01P] - Analysis of RNF135 expression in human liver.

RNF135 Antibody - H00084282-B01 from Novus Biologicals

Prices	$349.00
Sizes	50 µl
Host	Mouse
Clonality	Polyclonal

Western Blot: RNF135 Antibody [H00084282-B01] - analysis of RNF135 expression in transfected 293T cell line by RNF135 MaxPab polyclonal antibody (B01). Lane 1: RNF135 transfected lysate (22.90 KDa). Lane 2: Non-transfected lysate.

RNF135 Polyclonal Antibody - bs-11753R from Bioss

Prices	$269.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

RNF135 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-11753R-A350 from Bioss

Prices	$369.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

RNF135 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-11753R-A488 from Bioss

Prices	$369.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

RNF135 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-11753R-A555 from Bioss

Prices	$369.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

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