RNF135

Gene Symbol RNF135
Entrez Gene 84282
Alt Symbol L13, MMFD, REUL, Riplet
Species Human
Gene Type protein-coding
Description ring finger protein 135
Other Description E3 ubiquitin-protein ligase RNF135|RIG-I E3 ubiquitin ligase
Swissprots F5GX60 A0AVM5 B2R7G9 B6ZLM5 Q9BSE9 Q8IUD6
Accessions EAW80286 Q8IUD6 AB470605 BAG84604 AI634044 AJ496729 CAD43140 AK122646 BAG53638 AK122709 BAG53681 AK226030 AK312979 BAG35816 AY598332 AAT06743 BC005084 AAH05084 BC082262 BC126420 AAI26421 BC126422 AAI26423 BC144143 DA878616 XM_005258043 XP_005258100 XM_006722138 XP_006722201 NM_001184992 NP_001171921 NM_032322 NP_115698 NM_197939 NP_922921
Function Acts as an E2-dependent E3 ubiquitin-protein ligase, involved in innate immune defense against viruses. Ubiquitinates DDX58 and is required for full activation of the DDX58 signaling resulting in interferon beta production. {ECO:0000269|PubMed:19017631, ECO:0000269|PubMed:19484123}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:19484123}.
Tissue Specificity Expressed in skeletal muscle, spleen, kidney, placenta, prostate, stomach, thyroid and tongue. Also weakly expressed in heart, thymus, liver and lung. {ECO:0000269|PubMed:19017631}.

Human RNF135 full length protein - ab164552 from Abcam

Category Protein
Source Wheat germ
Species Human
ab164552 on a 12.5% SDS-PAGE stained with Coomassie Blue.

RNF135 Antibody Blocking Peptide - LS-E12312 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

RNF135 Antibody Blocking Peptide - LS-E6594 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

RNF135 Antibody Blocking Peptide - LS-E12429 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

RNF135 Antibody Blocking Peptide - LS-E12430 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human RNF135 Protein - H00084282-P01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

RNF135-AntibodyC-term-Blocking-peptide - BP19376b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

MRPL13 protein (His tag) - 80R-2722 from Fitzgerald

Category Protein
Prices $270.00
Sizes 100 µg
Source E.coli

RNF135 - H00084282-P01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

RNF135 - H00084282-P01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

RNF135 fusion protein - ag18816 from Proteintech Group

Category Protein
Source E. coli-derived, PGEX-4T
Species Human

RNF135 fusion protein - Ag18821 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PET28a
Species Human

Recombinant Human E3 ubiquitin-protein ligase RNF135(RNF135) - CSB-YP811599HU CSB-EP811599HU CSB-BP811599HU CSB-MP811599HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

RNF135 (transcript variant 1) - TP319438 from Acris Antibodies

Category Protein
Prices $680.00
Sizes 20 µg
Source HEK293 cells
Species Human
RNF135

RNF135 (transcript variant 3) - TP329833 from Acris Antibodies

Category Protein
Prices $680.00
Sizes 20 µg
Source HEK293 cells
Species Human
RNF135

RNF135 Recombinant Protein Antigen - NBP1-81212PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

RNF135 Peptide, Human - M34GP13383H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

RNF135 Recombinant Protein Antigen - NBP2-56223PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

E3 ubiquitin-protein ligase RNF135 (RNF135), Recombinant Protein - MBS1411302 from MyBioSource

Category Protein
Prices $1,210.00, $1,210.00, $1,430.00, $1,430.00, $1,955.00, $1,955.00, $2,420.00, $2,420.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human
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