RNF135

Gene Symbol	RNF135
Entrez Gene	84282
Alt Symbol	L13, MMFD, REUL, Riplet
Species	Human
Gene Type	protein-coding
Description	ring finger protein 135
Other Description	E3 ubiquitin-protein ligase RNF135|RIG-I E3 ubiquitin ligase
Swissprots	F5GX60 A0AVM5 B2R7G9 B6ZLM5 Q9BSE9 Q8IUD6
Accessions	EAW80286 Q8IUD6 AB470605 BAG84604 AI634044 AJ496729 CAD43140 AK122646 BAG53638 AK122709 BAG53681 AK226030 AK312979 BAG35816 AY598332 AAT06743 BC005084 AAH05084 BC082262 BC126420 AAI26421 BC126422 AAI26423 BC144143 DA878616 XM_005258043 XP_005258100 XM_006722138 XP_006722201 NM_001184992 NP_001171921 NM_032322 NP_115698 NM_197939 NP_922921
Function	Acts as an E2-dependent E3 ubiquitin-protein ligase, involved in innate immune defense against viruses. Ubiquitinates DDX58 and is required for full activation of the DDX58 signaling resulting in interferon beta production. {ECO:0000269|PubMed:19017631, ECO:0000269|PubMed:19484123}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:19484123}.
Tissue Specificity	Expressed in skeletal muscle, spleen, kidney, placenta, prostate, stomach, thyroid and tongue. Also weakly expressed in heart, thymus, liver and lung. {ECO:0000269|PubMed:19017631}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

RNF135 CRISPR/Cas9 KO Plasmid (h) - sc-408979 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

RNF135 HDR Plasmid (h) - sc-408979-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

RNF135 Double Nickase Plasmid (h) - sc-408979-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

RNF135 Double Nickase Plasmid (h2) - sc-408979-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

RNF135 CRISPR Activation Plasmid (h) - sc-408979-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

RNF135 CRISPR Activation Plasmid (h2) - sc-408979-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

RNF135 Lentiviral Activation Particles (h) - sc-408979-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

RNF135 Lentiviral Activation Particles (h2) - sc-408979-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

RNF135 siRNA (h) - sc-94030 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

RNF135 shRNA Plasmid (h) - sc-94030-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

RNF135 shRNA (h) Lentiviral Particles - sc-94030-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

RNF135 RNAi - H00084282-R02 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

RNF135 RNAi - H00084282-R01 from Novus Biologicals Category siRNA Prices $409.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU133761 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN2509 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2509 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR08468 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr08468

RNF135 siRNA (Human) - CRJ3407 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

RNF135 - MBS8229678 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human RNF135 (NM_197939.1) - SHH396712 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human RNF135(NM_197939.1) - SHR185404 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human RNF135(NM_032322.3) - SHR185458 from Creative biogene Category siRNA Species Reactivities Human

RNF135 shRNA Plasmid (Human) - CHJ3407 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

RNF135 miRNA 3'UTR clone - MiUTR1H-08878 from Creative biogene Species Reactivities Human

RNF135 miRNA 3'UTR clone - MiUTR1H-08879 from Creative biogene Species Reactivities Human

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