HTR1D

Gene Symbol HTR1D
Entrez Gene 3352
Alt Symbol 5-HT1D, HT1DA, HTR1DA, HTRL, RDC4
Species Human
Gene Type protein-coding
Description 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
Other Description 5-HT-1D|5-HT-1D-alpha|5-hydroxytryptamine receptor 1D|serotonin 1D alpha receptor|serotonin receptor 1D
Swissprots P28221
Accessions AAA35491 EAW95037 P28221 AF498979 AAM21126 BC007720 AAH07720 BT007027 AAP35673 DQ893875 ABM84801 EU176172 ABW03623 M81589 AAA60315 NM_000864 NP_000855
Function G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for ergot alkaloid derivatives, various anxiolytic and antidepressant drugs and other psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. Regulates the release of 5-hydroxytryptamine in the brain, and thereby affects neural activity. May also play a role in regulating the release of other neurotransmitters. May play a role in vasoconstriction. {ECO:0000269|PubMed:10452531, ECO:0000269|PubMed:1565658, ECO:0000269|PubMed:1652050}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:10452531, ECO:0000269|PubMed:1565658, ECO:0000269|PubMed:1652050}; Multi- pass membrane protein {ECO:0000269|PubMed:10452531, ECO:0000269|PubMed:1565658, ECO:0000269|PubMed:1652050}.
Tissue Specificity Detected in brain neocortex and caudate nucleus (at protein level). {ECO:0000269|PubMed:1828434}.
Top Pathways cAMP signaling pathway, Neuroactive ligand-receptor interaction

SR-1D (H-4) - sc-398809 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
SR-1D (H-4): sc-398809. Western blot analysis of SR-1D expression in SH-SY5Y whole cell lysate (A) and mouse brain tissue extract (B).

SR-1D (C-18) - sc-1463 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
SR-1D (C-18): sc-1463. Western blot analysis of SR-1D expression in HeLa (A) and ES-2 (B) whole cell lysates.

SR-1D (H-70) - sc-25644 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
SR-1D (H-70): sc-25644. Western blot analysis of SR-1D expression in T98G (A), SH-SY5Y (B) and EOC 13.31 (C) whole cell lysates and mouse brain tissue extract (D).

SR-1D (S-18) - sc-5393 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
SR-1D (S-18): sc-5393. Western blot analysis of SR-1D expression in HeLa (A), CCRF-CEM (B) and ES-2 (C) whole cell lysates.

Anti-5HT1D Receptor antibody - ab13895 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-5HT1D Receptor antibody - C-terminal - ab138990 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-5HT1D Receptor antibody - C-terminal (ab138990) at 1/100 dilution + Mouse stomach tissue lysates at 35 µgdeveloped using the ECL technique

Anti-HTR1D / 5-HT1D Receptor Antibody (aa1-18) - LS-C91316 from LifeSpan Bioscience

Prices $485.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-HTR1D / 5-HT1D Receptor Antibody (aa271-301, AP) - LS-C222773 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HTR1D / 5-HT1D Receptor Antibody (aa271-301, Biotin) - LS-C222776 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HTR1D / 5-HT1D Receptor Antibody (aa271-301, APC) - LS-C222775 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HTR1D / 5-HT1D Receptor Antibody (aa271-301, PE) - LS-C222778 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HTR1D / 5-HT1D Receptor Antibody (aa271-301) - LS-C329648 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HTR1D / 5-HT1D Receptor Antibody (aa272-301) - LS-C159874 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
HTR1D Antibody western blot of mouse stomach tissue lysates (35 ug/lane). The HTR1D antibody detected the HTR1D protein (arrow).

Anti-HTR1D / 5-HT1D Receptor Antibody - LS-C340926 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-HTR1D / 5-HT1D Receptor Antibody (aa271-301, FITC) - LS-C222777 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HTR1D / 5-HT1D Receptor Antibody (aa271-301, Azide-free, HRP) - LS-C222779 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HTR1D / 5-HT1D Receptor Antibody (Extracellular Domain) IHC-plus™ - LS-A590 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-5HT1D Receptor antibody LS-A590 IHC of human spinal cord, dorsal root ganglion. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-HTR1D / 5-HT1D Receptor Antibody (Cytoplasmic Domain) IHC-plus™ - LS-A577 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-5HT1D Receptor antibody LS-A577 IHC of human spinal cord, dorsal root ganglion. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-HTR1D / 5-HT1D Receptor Antibody (Cytoplasmic Domain) IHC-plus™ - LS-A589 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-5HT1D Receptor antibody LS-A589 IHC of human spinal cord, dorsal root ganglion. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-HTR1D / 5-HT1D Receptor Antibody (N-Terminus) IHC-plus™ - LS-A588 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-5HT1D Receptor antibody LS-A588 IHC of human spinal cord, dorsal root ganglion. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-HTR1D / 5-HT1D Receptor Antibody (aa1-18) IHC-plus™ - LS-B2041 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-5HT1D Receptor antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2041 concentration 10 ug/ml.

5-HT1D Antibody - NBP1-46540 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

5-HT1D Antibody - NBP2-21591 from Novus Biologicals

Host Rabbit
Clonality Polyclonal

5-HT1D Antibody - NLS588 from Novus Biologicals

Prices $329.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: 5-HT1D Antibody [NLS588] - Analysis of anti-5HT1D Receptor antibody with human spinal cord, dorsal root ganglion.

5-HT1D Antibody - NLS590 from Novus Biologicals

Prices $329.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
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