HTR1D

Gene Symbol HTR1D
Entrez Gene 3352
Alt Symbol 5-HT1D, HT1DA, HTR1DA, HTRL, RDC4
Species Human
Gene Type protein-coding
Description 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
Other Description 5-HT-1D|5-HT-1D-alpha|5-hydroxytryptamine receptor 1D|serotonin 1D alpha receptor|serotonin receptor 1D
Swissprots P28221
Accessions AAA35491 EAW95037 P28221 AF498979 AAM21126 BC007720 AAH07720 BT007027 AAP35673 DQ893875 ABM84801 EU176172 ABW03623 M81589 AAA60315 NM_000864 NP_000855
Function G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for ergot alkaloid derivatives, various anxiolytic and antidepressant drugs and other psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. Regulates the release of 5-hydroxytryptamine in the brain, and thereby affects neural activity. May also play a role in regulating the release of other neurotransmitters. May play a role in vasoconstriction. {ECO:0000269|PubMed:10452531, ECO:0000269|PubMed:1565658, ECO:0000269|PubMed:1652050}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:10452531, ECO:0000269|PubMed:1565658, ECO:0000269|PubMed:1652050}; Multi- pass membrane protein {ECO:0000269|PubMed:10452531, ECO:0000269|PubMed:1565658, ECO:0000269|PubMed:1652050}.
Tissue Specificity Detected in brain neocortex and caudate nucleus (at protein level). {ECO:0000269|PubMed:1828434}.
Top Pathways cAMP signaling pathway, Neuroactive ligand-receptor interaction

5-hydroxytryptamine (serotonin) receptor 1D, ELISA Kit - MBS9328005 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

5-hydroxytryptamine receptor 1D, ELISA Kit - MBS280927 from MyBioSource

Category ELISA Kit
Prices $465.00, $790.00, $3,500.00, $6,655.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

5-hydroxytryptamine receptor 1D, ELISA Kit - MBS281453 from MyBioSource

Category ELISA Kit
Prices $425.00, $720.00, $3,160.00, $6,055.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 0.1 ng/mL (mean of 6 independent assays).
Range 0.31 ng/mL - 20 ng/mL.

Human HTR1D ELISA Kit - E042068 from Biobool

Category ELISA Kit

5-hydroxytryptamine receptor 1D, ELISA Kit - MBS285316 from MyBioSource

Category ELISA Kit
Prices $465.00, $790.00, $3,500.00, $6,655.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

5-hydroxytryptamine receptor 1D, ELISA Kit - MBS284448 from MyBioSource

Category ELISA Kit
Prices $465.00, $790.00, $3,500.00, $6,655.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
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