HTR1D

Gene Symbol HTR1D
Entrez Gene 3352
Alt Symbol 5-HT1D, HT1DA, HTR1DA, HTRL, RDC4
Species Human
Gene Type protein-coding
Description 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
Other Description 5-HT-1D|5-HT-1D-alpha|5-hydroxytryptamine receptor 1D|serotonin 1D alpha receptor|serotonin receptor 1D
Swissprots P28221
Accessions AAA35491 EAW95037 P28221 AF498979 AAM21126 BC007720 AAH07720 BT007027 AAP35673 DQ893875 ABM84801 EU176172 ABW03623 M81589 AAA60315 NM_000864 NP_000855
Function G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for ergot alkaloid derivatives, various anxiolytic and antidepressant drugs and other psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. Regulates the release of 5-hydroxytryptamine in the brain, and thereby affects neural activity. May also play a role in regulating the release of other neurotransmitters. May play a role in vasoconstriction. {ECO:0000269|PubMed:10452531, ECO:0000269|PubMed:1565658, ECO:0000269|PubMed:1652050}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:10452531, ECO:0000269|PubMed:1565658, ECO:0000269|PubMed:1652050}; Multi- pass membrane protein {ECO:0000269|PubMed:10452531, ECO:0000269|PubMed:1565658, ECO:0000269|PubMed:1652050}.
Tissue Specificity Detected in brain neocortex and caudate nucleus (at protein level). {ECO:0000269|PubMed:1828434}.
Top Pathways cAMP signaling pathway, Neuroactive ligand-receptor interaction

SR-1D CRISPR/Cas9 KO Plasmid (h) - sc-404213 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SR-1D HDR Plasmid (h) - sc-404213-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SR-1D Double Nickase Plasmid (h) - sc-404213-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SR-1D Double Nickase Plasmid (h2) - sc-404213-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SR-1D CRISPR Activation Plasmid (h) - sc-404213-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SR-1D CRISPR Activation Plasmid (h2) - sc-404213-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SR-1D Lentiviral Activation Particles (h) - sc-404213-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SR-1D Lentiviral Activation Particles (h2) - sc-404213-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SR-1D siRNA (h) - sc-42225 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SR-1D shRNA Plasmid (h) - sc-42225-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SR-1D shRNA (h) Lentiviral Particles - sc-42225-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

5-HT1D RNAi - H00003352-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU153981 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN10392 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10392 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

HTR1D siRNA (Human) - CRH2283 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

HTR1D - MBS827000 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human HTR1D (NM_000864.4) - SHH315885 from Creative biogene

Category siRNA
Species Reactivities Human

Human HTR1D siRNA - orb262785 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

HTR1D shRNA Plasmid (Human) - CHH2283 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

HTR1D miRNA 3'UTR clone - MiUTR4H-TG04358 from Creative biogene

Species Reactivities Human
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