HTR1D

Gene Symbol	HTR1D
Entrez Gene	3352
Alt Symbol	5-HT1D, HT1DA, HTR1DA, HTRL, RDC4
Species	Human
Gene Type	protein-coding
Description	5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
Other Description	5-HT-1D|5-HT-1D-alpha|5-hydroxytryptamine receptor 1D|serotonin 1D alpha receptor|serotonin receptor 1D
Swissprots	P28221
Accessions	AAA35491 EAW95037 P28221 AF498979 AAM21126 BC007720 AAH07720 BT007027 AAP35673 DQ893875 ABM84801 EU176172 ABW03623 M81589 AAA60315 NM_000864 NP_000855
Function	G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for ergot alkaloid derivatives, various anxiolytic and antidepressant drugs and other psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. Regulates the release of 5-hydroxytryptamine in the brain, and thereby affects neural activity. May also play a role in regulating the release of other neurotransmitters. May play a role in vasoconstriction. {ECO:0000269|PubMed:10452531, ECO:0000269|PubMed:1565658, ECO:0000269|PubMed:1652050}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:10452531, ECO:0000269|PubMed:1565658, ECO:0000269|PubMed:1652050}; Multi- pass membrane protein {ECO:0000269|PubMed:10452531, ECO:0000269|PubMed:1565658, ECO:0000269|PubMed:1652050}.
Tissue Specificity	Detected in brain neocortex and caudate nucleus (at protein level). {ECO:0000269|PubMed:1828434}.
Top Pathways	cAMP signaling pathway, Neuroactive ligand-receptor interaction

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human 5HT1D Receptor full length protein - ab158712 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

HTR1D / 5-HT1D Receptor Antibody Blocking Peptide - LS-E6423 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

HTR1D / 5-HT1D Receptor Antibody Blocking Peptide - LS-E29099 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

HTR1D / 5-HT1D Receptor Antibody Blocking Peptide - LS-E29105 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

HTR1D / 5-HT1D Receptor Antibody Blocking Peptide - LS-E29107 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

HTR1D / 5-HT1D Receptor Antibody Blocking Peptide - LS-E29106 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

Recombinant Human 5-HT1D Protein - H00003352-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

HTR1D-Antibody-C-term-Blocking-Peptide - BP19163b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

5-HT1D Blocking Peptide - abx062757 from Abbexa Category Peptide Species Human, Mouse, Rat

Serotonin receptor 1D (HTR1D) - H00003352-G01 from Acris Antibodies Category Protein Prices $440.00 Sizes 2 µg Species Human

Serotonin receptor 1D (HTR1D) - H00003352-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Serotonin receptor 1D (HTR1D) - H00003352-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

HTR1D fusion protein - ag9289 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

5-HT1D Blocking Peptide - CBP1563 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat

Recombinant Human 5-HT1D Protein - H00003352-G01 from Novus Biologicals Category Protein Prices $415.00 Sizes 2 µg Source Wheat Germ Species Human

5-hydroxytryptamine receptor 1D (HTR1D), Recombinant Protein - MBS956903 from MyBioSource Category Protein Prices $1,375.00, $1,835.00 Sizes 1 mg (E-Coli), 1 mg (Yeast) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

HTR1D Peptide, Human - M34GP07339H from Creative Peptides Category Peptide Source Synthetic. Species Human

5-hydroxytryptamine receptor 1D (HTR1D), Recombinant Protein - MBS7017268 from MyBioSource Category Protein Prices $1,185.00, $2,170.00, $3,380.00 Sizes 10 µg, 50 µg, 100 µg Source Cell Free Expression Species Human

HTR1D fusion protein - Ag25276 from Proteintech Group Category Protein Source E. coli -derived, PET30a Species Human

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