MALT1

Gene Symbol	MALT1
Entrez Gene	10892
Alt Symbol	IMD12, MLT, MLT1
Species	Human
Gene Type	protein-coding
Description	MALT1 paracaspase
Other Description	MALT lymphoma-associated translocation|MALT1 protease|caspase-like protein|mucosa associated lymphoid tissue lymphoma translocation gene 1|mucosa-associated lymphoid tissue lymphoma translocation protein 1|paracaspase
Swissprots	Q9UDY8 Q9ULX4 Q9NTB7
Accessions	EAW63078 EAW63079 Q9UDY8 AB026118 BAA83099 AF070528 AF130356 AAD38507 AF316597 AAG38589 AK024859 AK092004 AK291386 BAF84075 AL137399 CAB70725 BC030143 AAH30143 DQ892319 ABM83245 DQ895521 ABM86447 XM_011525794 XP_011524096 XR_935190 NM_006785 NP_006776 NM_173844 NP_776216
Function	Enhances BCL10-induced activation of NF-kappa-B. Involved in nuclear export of BCL10. Binds to TRAF6, inducing TRAF6 oligomerization and activation of its ligase activity. Has ubiquitin ligase activity. MALT1-dependent BCL10 cleavage plays an important role in T-cell antigen receptor-induced integrin adhesion. {ECO:0000269|PubMed:11262391, ECO:0000269|PubMed:14695475, ECO:0000269|PubMed:18264101}.
Subcellular Location	Cytoplasm, perinuclear region {ECO:0000269|PubMed:16123224}. Nucleus {ECO:0000269|PubMed:16123224}. Note=Shuttles between the nucleus and cytoplasm. Found in perinuclear structures together with BCL10.
Tissue Specificity	Highly expressed in peripheral blood mononuclear cells. Detected at lower levels in bone marrow, thymus and lymph node, and at very low levels in colon and lung.
Top Pathways	T cell receptor signaling pathway, B cell receptor signaling pathway, Tuberculosis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human MALT1 full length protein - ab161189 from Abcam Category Protein Source Wheat germ Species Human

Human MALT1 protein fragment - ab161190 from Abcam Category Protein Source Wheat germ Species Human

MALT1 Antibody Blocking Peptide - LS-E27707 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human MALT1 Protein - H00010892-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human MALT1 Protein - H00010892-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

MALT1 - H00010892-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

MALT1 - H00010892-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

MALT1 - H00010892-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

MALT1 - H00010892-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

MALT1 Peptide - 8097P from ProSci Category Peptide Species Human

MALT1 fusion protein - Ag2182 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

MALT1 fusion protein - Ag20632 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human MALT1, GST-tagged - MALT1-717H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human MALT1, GST-tagged - MALT1-27H from Creative Biomart Category Protein Source Wheat germ Species Human

Recombinant Human MALT1, MYC/DDK-tagged - MALT1-28H from Creative Biomart Category Protein Source HEK293 cells Species Human

MALT1 (N324) Peptide - BS2534P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Human Mucosa-associated lymphoid tissue lymphoma translocation protein 1(MALT1) ,partial - CSB-YP866213HU CSB-EP866213HU CSB-BP866213HU CSB-MP866213HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

MALT1 (transcript variant 2) - TP304322 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

MALT1 (transcript variant 1) - TP314639 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Recombinant Human MALT1 protein, His/Thioredoxin-tagged - MALT1-857H from Creative Biomart Category Protein Source E. coli Species Human

MALT1 Protein - NBP1-87385PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

MALT1 Peptide, Human - M34GP09124H from Creative Peptides Category Peptide Source Synthetic. Species Human

MALT1 Recombinant Protein Antigen - NBP2-55513PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1), partial, Recombinant Protein - MBS1304557 from MyBioSource Category Protein Prices $640.00, $780.00, $860.00, $930.00, $945.00, $1,050.00, $1,170.00, $1,170.00, $1,185.00, $1,330.00, $1,690.00, $1,775.00, $1,805.00, $2,255.00 Sizes 50 µg (E-Coli), 50 µg (Yeast), 200 µg (E-Coli), 50 µg (Baculovirus), 500 µg (E-Coli), 200 µg (Yeast), 100 µg (Baculovirus), 50 µg (Mammalian-Cell), 500 µg (Yeast), 1 mg (E-Coli), 500 µg (Baculovirus), 100 µg (Mammalian-Cell), 1 mg (Yeast), 1 mg (Baculovirus) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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