GM2A

Gene Symbol	GM2A
Entrez Gene	2760
Alt Symbol	GM2-AP, SAP-3
Species	Human
Gene Type	protein-coding
Description	GM2 ganglioside activator
Other Description	cerebroside sulfate activator protein|ganglioside GM2 activator|shingolipid activator protein 3|sphingolipid activator protein 3
Swissprots	D3DQH6 Q14428 Q14426 Q6LBL5 B2R699 P17900
Accessions	AAD25741 AAF63788 EAW61680 EAW61681 P17900 AK225978 AK298867 BAG60987 AK312494 BAG35396 BC009273 AAH09273 BM834780 BX473154 DQ891914 ABM82840 DQ895098 ABM86024 L01439 AAA52767 M76477 AAA35907 X16087 CAA34215 X61094 CAA43407 X61095 CAA43408 X62078 CAA43993 NM_000405 NP_000396 NM_001167607 NP_001161079
Function	The large binding pocket can accommodate several single chain phospholipids and fatty acids, GM2A also exhibits some calcium-independent phospholipase activity (By similarity). Binds gangliosides and stimulates ganglioside GM2 degradation. It stimulates only the breakdown of ganglioside GM2 and glycolipid GA2 by beta-hexosaminidase A. It extracts single GM2 molecules from membranes and presents them in soluble form to beta- hexosaminidase A for cleavage of N-acetyl-D-galactosamine and conversion to GM3. {ECO:0000250}.
Subcellular Location	Lysosome.
Top Pathways	Lysosome

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human GM2A Gene cDNA Clone - orb143392 from Biorbyt Prices $255.00 Sizes 10 μg Species Human

Human-GM2A-cDNA-Clone - DC02610 from Abgent, a WuXi AppTec company Prices $260.55 Sizes 10 µg Species Human Accession BC009273

GM2A - MBS1278949 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC009273

Human GM2A cDNA clone(NM_001167607.1) - CDFH007680 from Creative Biomart Species Human Accession NM_001167607.1

Human GM2A ORF Clone(NM_001167607.1) - CDCR355503 from Creative Biomart Species Human Accession NM_001167607.1

Human GM2A ORF Clone(NM_001167607.1) - CDCR355504 from Creative Biomart Species Human Accession NM_001167607.1

Human GM2A ORF Clone(NM_000405.4) - CDCL164829 from Creative Biomart Species Human Accession NM_000405.4

Human GM2A Gene ORF cDNA clone in cloning vector - HG13246-G from Sino Biological Species Human

Human GM2A Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG13246-ACR from Sino Biological Species Human

Human GM2A Gene ORF cDNA clone expression plasmid, C-His tag - HG13246-CH from Sino Biological Species Human

Human GM2A Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG13246-ACG from Sino Biological Species Human

Human GM2A Gene ORF cDNA clone expression plasmid - HG13246-UT from Sino Biological Species Human

Human GM2A Gene ORF cDNA clone expression plasmid, C-HA tag - HG13246-CY from Sino Biological Species Human

Human GM2A Gene ORF cDNA clone expression plasmid, N-HA tag - HG13246-NY from Sino Biological Species Human

Human GM2A Gene ORF cDNA clone expression plasmid, N-Flag tag - HG13246-NF from Sino Biological Species Human

Human GM2A Gene ORF cDNA clone expression plasmid, N-His tag - HG13246-NH from Sino Biological Species Human

Human GM2A Gene ORF cDNA clone expression plasmid, N-Myc tag - HG13246-NM from Sino Biological Species Human

Human GM2A Gene ORF cDNA clone expression plasmid, C-Flag tag - HG13246-CF from Sino Biological Species Human

Human GM2A Gene ORF cDNA clone expression plasmid, C-Myc tag - HG13246-CM from Sino Biological Species Human

Mouse GM2A ORF clone (NM_000405.4) - CDCL112555 from Creative biogene Species Human

Mouse GM2A ORF clone (NM_001167607.1) - CDCL112557 from Creative biogene Species Human

Human GM2A ORF Clone (BC009273) - CDCS405643 from Creative biogene Species Human Accession P17900

Human GM2A ORF clone (BC009273) - CDCB160087 from Creative biogene Species Human

Human GM2A cDNA Clone(NM_001167607.1) - CDFH007680 from Creative biogene Species Human

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