GM2A

Gene Symbol	GM2A
Entrez Gene	2760
Alt Symbol	GM2-AP, SAP-3
Species	Human
Gene Type	protein-coding
Description	GM2 ganglioside activator
Other Description	cerebroside sulfate activator protein|ganglioside GM2 activator|shingolipid activator protein 3|sphingolipid activator protein 3
Swissprots	D3DQH6 Q14428 Q14426 Q6LBL5 B2R699 P17900
Accessions	AAD25741 AAF63788 EAW61680 EAW61681 P17900 AK225978 AK298867 BAG60987 AK312494 BAG35396 BC009273 AAH09273 BM834780 BX473154 DQ891914 ABM82840 DQ895098 ABM86024 L01439 AAA52767 M76477 AAA35907 X16087 CAA34215 X61094 CAA43407 X61095 CAA43408 X62078 CAA43993 NM_000405 NP_000396 NM_001167607 NP_001161079
Function	The large binding pocket can accommodate several single chain phospholipids and fatty acids, GM2A also exhibits some calcium-independent phospholipase activity (By similarity). Binds gangliosides and stimulates ganglioside GM2 degradation. It stimulates only the breakdown of ganglioside GM2 and glycolipid GA2 by beta-hexosaminidase A. It extracts single GM2 molecules from membranes and presents them in soluble form to beta- hexosaminidase A for cleavage of N-acetyl-D-galactosamine and conversion to GM3. {ECO:0000250}.
Subcellular Location	Lysosome.
Top Pathways	Lysosome

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

GM2A peptide - ab127733 from Abcam Category Peptide Prices $176.00 Sizes 100 µg

Human GM2A full length protein - ab178464 from Abcam Category Protein Source E. coli Species Human

Human GM2A full length protein - ab116790 from Abcam Category Protein Source Wheat germ Species Human

Human GM2A protein fragment - ab116791 from Abcam Category Protein Source Wheat germ Species Human

GM2A Antibody Blocking Peptide - LS-E8000 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

GM2A Antibody Blocking Peptide - LS-E27496 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

GM2A Antibody Blocking Peptide - LS-E27497 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

GM2A Antibody Blocking Peptide - LS-E29521 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

GM2A Antibody Blocking Peptide - LS-E29522 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

GM2A Antibody Blocking Peptide - LS-E29523 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

GM2A Antibody Blocking Peptide - LS-E16757 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

GM2A Antibody Blocking Peptide - LS-E16756 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

GM2A Antibody Blocking Peptide - LS-E29782 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

Recombinant Human GM2A Protein - H00002760-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

GM2A Recombinant Protein - H00002760-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

GM2A-Antibody-N-term-Blocking-peptide - BP5841a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant human Ganglioside GM2 activator protein (OPCA00447) - OPCA00447 from Aviva Systems Biology Category Protein Prices $220.00 Sizes 50 µg Species Human

Human Cerebroside sulfate activator protein - orb138928 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 10 μg, 20 μg Source Baculovirus-Insect Cells Species Human

Human GM2A protein - orb245125 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

Human GM2A protein - orb191230 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 2 μg, 10 μg Source E. coli Species Human

Goat anti GM2A antibody Immunizing peptide - orb66131 from Biorbyt Category Peptide Prices $247.00 Sizes 100 μg Species Human, Mouse, Rat

GM2A Blocking Peptide - 33R-8939 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

GM2A Blocking Peptide - 33R-6345 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

GM2A Peptide - AC21-2319-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

GM2A Peptide - AC21-2320-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

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