FBP2

Gene Symbol	FBP2
Entrez Gene	8789
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	fructose-1,6-bisphosphatase 2
Other Description	D-fructose-1,6-bisphosphate 1-phosphohydrolase 2|FBPase 2|fructose-1,6-bisphosphatase isozyme 2|hexosediphosphatase|muscle FBPase|muscle fructose-bisphosphatase
Swissprots	Q6FI53 Q17R39 O00757
Accessions	CAB53359 CAB53360 CAB53361 CAB53362 CAB53363 CAB53364 CAB53365 CAB53366 CAB58560 CAB58561 EAW92616 O00757 AJ573829 BC113632 AAI13633 BC117477 AAI17478 BM686555 BU727940 CR536483 CAG38722 HQ258389 ADR83143 Y10812 CAA71772 XM_011519164 XP_011517466 NM_003837 NP_003828
Function	Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations and probably participates in glycogen synthesis from carbohydrate precursors, such as lactate. {ECO:0000269|PubMed:17350621, ECO:0000269|PubMed:18214967}.
Subcellular Location	Cell junction {ECO:0000250}. Cytoplasm. Nucleus. Cytoplasm, myofibril, sarcomere, Z line. Note=In neonatal cardiomyocytes, distributed throughout the cytosol, accumulating in the intercalated disks which occur at the Z line of cardiomyocytes and connect adjacent cells, and also located in the nucleus; dissociates from the Z line following an increase in cytosolic Ca(2+) concentration (By similarity). In muscle precursor cells, localizes predominantly to the nucleus and to a lesser extent to the cytoplasm at the proliferative phase, while mainly localizing to the cytoplasm at the differentiation phase (By similarity). Colocalizes with ALDOA and alpha-actinin on both sides of the Z line of skeletal muscle; dissociates rapidly from the Z line following an increase in cytosolic Ca(2+) concentration. {ECO:0000250}.
Tissue Specificity	Expressed in skeletal muscle (at protein level). {ECO:0000269|PubMed:12507293}.
Top Pathways	Glycolysis / Gluconeogenesis, Pentose phosphate pathway, Insulin signaling pathway, AMPK signaling pathway, Carbon metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-FBP2-cDNA-Clone - DC09854 from Abgent, a WuXi AppTec company Prices $457.65 Sizes 10 µg Species Human Accession BC113632

FBP2 - MBS1272980 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC113632

Human FBP2 cDNA clone(NM_003837.2) - CDFH006649 from Creative Biomart Species Human Accession NM_003837.2

Human FBP2 ORF Clone(NM_003837.2) - CDCL163187 from Creative Biomart Species Human Accession NM_003837.2

Human FBP2 ORF Clone(NM_003837.2) - CDCR286584 from Creative Biomart Species Human Accession NM_003837.2

Human FBP2 ORF Clone(NM_003837.2) - CDCR286585 from Creative Biomart Species Human Accession NM_003837.2

Human FBP2 ORF clone - CDCL107019 from Creative Biomart Species Human Accession NM_003837

Human FBP2 ORF clone - CDCL107020 from Creative Biomart Species Human Accession NM_003837

Human FBP2 Gene ORF cDNA clone in cloning vector - HG13899-G from Sino Biological Species Human

Human FBP2 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG13899-NF from Sino Biological Species Human

Human FBP2 Gene ORF cDNA clone expression plasmid, N-HA tag - HG13899-NY from Sino Biological Species Human

Human FBP2 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG13899-NM from Sino Biological Species Human

Human FBP2 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG13899-CF from Sino Biological Species Human

Human FBP2 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG13899-ACG from Sino Biological Species Human

Human FBP2 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG13899-CM from Sino Biological Species Human

Human FBP2 Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG13899-ANG from Sino Biological Species Human

Human FBP2 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG13899-ACR from Sino Biological Species Human

Human FBP2 Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG13899-ANR from Sino Biological Species Human

Human FBP2 Gene ORF cDNA clone expression plasmid, C-HA tag - HG13899-CY from Sino Biological Species Human

Human FBP2 Gene ORF cDNA clone expression plasmid - HG13899-UT from Sino Biological Species Human

Human FBP2 Gene ORF cDNA clone expression plasmid, N-His tag - HG13899-NH from Sino Biological Species Human

Human FBP2 Gene ORF cDNA clone expression plasmid, C-His tag - HG13899-CH from Sino Biological Species Human

Human FBP2 ORF Clone(NM_003837.2) - CDCR286584 from Creative biogene Species Human

Human FBP2 ORF Clone (BC113632) - CDCS411499 from Creative biogene Species Human Accession O00757

Human FBP2 cDNA Clone(NM_003837.2) - CDFH006649 from Creative biogene Species Human

Search more