FBP2

Gene Symbol	FBP2
Entrez Gene	8789
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	fructose-1,6-bisphosphatase 2
Other Description	D-fructose-1,6-bisphosphate 1-phosphohydrolase 2|FBPase 2|fructose-1,6-bisphosphatase isozyme 2|hexosediphosphatase|muscle FBPase|muscle fructose-bisphosphatase
Swissprots	Q6FI53 Q17R39 O00757
Accessions	CAB53359 CAB53360 CAB53361 CAB53362 CAB53363 CAB53364 CAB53365 CAB53366 CAB58560 CAB58561 EAW92616 O00757 AJ573829 BC113632 AAI13633 BC117477 AAI17478 BM686555 BU727940 CR536483 CAG38722 HQ258389 ADR83143 Y10812 CAA71772 XM_011519164 XP_011517466 NM_003837 NP_003828
Function	Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations and probably participates in glycogen synthesis from carbohydrate precursors, such as lactate. {ECO:0000269|PubMed:17350621, ECO:0000269|PubMed:18214967}.
Subcellular Location	Cell junction {ECO:0000250}. Cytoplasm. Nucleus. Cytoplasm, myofibril, sarcomere, Z line. Note=In neonatal cardiomyocytes, distributed throughout the cytosol, accumulating in the intercalated disks which occur at the Z line of cardiomyocytes and connect adjacent cells, and also located in the nucleus; dissociates from the Z line following an increase in cytosolic Ca(2+) concentration (By similarity). In muscle precursor cells, localizes predominantly to the nucleus and to a lesser extent to the cytoplasm at the proliferative phase, while mainly localizing to the cytoplasm at the differentiation phase (By similarity). Colocalizes with ALDOA and alpha-actinin on both sides of the Z line of skeletal muscle; dissociates rapidly from the Z line following an increase in cytosolic Ca(2+) concentration. {ECO:0000250}.
Tissue Specificity	Expressed in skeletal muscle (at protein level). {ECO:0000269|PubMed:12507293}.
Top Pathways	Glycolysis / Gluconeogenesis, Pentose phosphate pathway, Insulin signaling pathway, AMPK signaling pathway, Carbon metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human FBP2 full length protein - ab137162 from Abcam Category Protein Source E. coli Species Human

FBP2-Antibody-C-term-Blocking-Peptide - BP6729b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

FBP2 (1-339, His-tag) - AR50632PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

FBP2 (1-339, His-tag) - AR50632PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

FBP2 - H00008789-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

FBP2 - H00008789-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

FBP2 - H00008789-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

FBP2 - H00008789-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

FBP2, 1-339 aa, Human, His tag, E.coli - 01-P1808 from ARP American Research Products Category Protein Prices $179.00, $369.00, $849.00 Sizes 20 µg, 100 µg, 500 µg Species Human

FBP2 fusion protein - Ag18245 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

FBP2 fusion protein - Ag18862 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

FBP2 Human - ENPS-674 from NeoScientific Category Protein Prices $65.00, $169.00, $3,510.00 Sizes 5 µg, 20 µg, 1 mg Source Escherichia Coli. Species Human

Recombinant Human FBP2, GST-tagged - FBP2-12769H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human fructose-1,6-bisphosphatase 2, His-tagged - FBP2-369H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Fructose-1,6-bisphosphatase isozyme 2(FBP2) - CSB-YP008460HU CSB-EP008460HU CSB-BP008460HU CSB-MP008460HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

FBP2, 1-339aa, Human, His tag, E.coli - ATGP1808 from ATGen Category Protein Prices $80.00, $240.00, $720.00 Sizes 20 µg, 100 µg, 500 µg Species Human

FBP2, human recombinant - 7804-100 from Biovision Category Protein Prices $295.00 Sizes 100 μg Source E. coli. Species Human

FBP2 (1-339, His-tag) - AR51990PU-N from Acris Antibodies Category Protein Prices $410.00 Sizes 100 µg Source E. coli Species Human

FBP2 (1-339, His-tag) - AR51990PU-S from Acris Antibodies Category Protein Prices $235.00 Sizes 20 µg Source E. coli Species Human

FBP2, 1-339aa, Human, His tag, E.coli (Bioactivity Validated) - ATGP3235 from ATGen Category Protein Prices $30.00, $105.00, $320.00 Sizes 4 µg, 20 µg, 100 µg Species Human

Fructose-1,6-Bisphosphatase 2 (Recombinant) - abx073372 from Abbexa

FBP2 - TP321146 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Recombinant Human FBP2 Protein, His-tagged - FBP2-390H from Creative Biomart Category Protein Source E.coli Species Human

FBP2, Recombinant Protein - MBS205436 from MyBioSource Category Protein Prices $310.00, $720.00 Sizes 100 µg, 500 µg Source E Coli Species Human

FBP2, Recombinant Protein - MBS844192 from MyBioSource Category Protein Prices $365.00 Sizes 100 µg Source E Coli

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