FBP2

Gene Symbol	FBP2
Entrez Gene	8789
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	fructose-1,6-bisphosphatase 2
Other Description	D-fructose-1,6-bisphosphate 1-phosphohydrolase 2|FBPase 2|fructose-1,6-bisphosphatase isozyme 2|hexosediphosphatase|muscle FBPase|muscle fructose-bisphosphatase
Swissprots	Q6FI53 Q17R39 O00757
Accessions	CAB53359 CAB53360 CAB53361 CAB53362 CAB53363 CAB53364 CAB53365 CAB53366 CAB58560 CAB58561 EAW92616 O00757 AJ573829 BC113632 AAI13633 BC117477 AAI17478 BM686555 BU727940 CR536483 CAG38722 HQ258389 ADR83143 Y10812 CAA71772 XM_011519164 XP_011517466 NM_003837 NP_003828
Function	Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations and probably participates in glycogen synthesis from carbohydrate precursors, such as lactate. {ECO:0000269|PubMed:17350621, ECO:0000269|PubMed:18214967}.
Subcellular Location	Cell junction {ECO:0000250}. Cytoplasm. Nucleus. Cytoplasm, myofibril, sarcomere, Z line. Note=In neonatal cardiomyocytes, distributed throughout the cytosol, accumulating in the intercalated disks which occur at the Z line of cardiomyocytes and connect adjacent cells, and also located in the nucleus; dissociates from the Z line following an increase in cytosolic Ca(2+) concentration (By similarity). In muscle precursor cells, localizes predominantly to the nucleus and to a lesser extent to the cytoplasm at the proliferative phase, while mainly localizing to the cytoplasm at the differentiation phase (By similarity). Colocalizes with ALDOA and alpha-actinin on both sides of the Z line of skeletal muscle; dissociates rapidly from the Z line following an increase in cytosolic Ca(2+) concentration. {ECO:0000250}.
Tissue Specificity	Expressed in skeletal muscle (at protein level). {ECO:0000269|PubMed:12507293}.
Top Pathways	Glycolysis / Gluconeogenesis, Pentose phosphate pathway, Insulin signaling pathway, AMPK signaling pathway, Carbon metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

muscle FBPase (E-11) - sc-390209 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

muscle FBPase (G-1) - sc-271799 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

muscle FBPase (C-12) - sc-32438 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

muscle FBPase (T-16) - sc-32437 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

muscle FBPase (Y-12) - sc-32436 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Anti-FBP2 antibody [EPR7435] - ab131333 from Abcam Prices $313.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPR7435

Anti-FBP2 antibody [EPR7436] - ab131253 from Abcam Prices $313.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPR7436

Anti-FBP2 Antibody (Internal, clone EPR7435) - LS-C154566 from LifeSpan Bioscience Prices $395.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPR7435

Anti-FBP2 Antibody (C-Terminus) - LS-C116352 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-FBP2 Antibody (aa216-265) - LS-C102272 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-FBP2 Antibody - LS-C310328 from LifeSpan Bioscience Prices $475.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-FBP2 Antibody (C-Terminus, clone EPR7436) - LS-C154553 from LifeSpan Bioscience Prices $395.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPR7436

Anti-FBP2 Antibody (clone AT1E11) - LS-C175820 from LifeSpan Bioscience Prices $315.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone AT1E11

Anti-FBP2 Antibody (aa250-281) - LS-C166065 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

FBP2 Antibody - NBP1-56453 from Novus Biologicals Prices $329.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

FBP2 Antibody - H00008789-D01P from Novus Biologicals Prices $399.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

FBP2 Antibody (1E11) - NBP2-22556 from Novus Biologicals Prices $279.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 1E11

FBP2 Antibody - H00008789-A01 from Novus Biologicals Prices $269.00 Sizes 50 µl Host Mouse Clonality Polyclonal

FBP2 Polyclonal Antibody - bs-3981R from Bioss Prices $269.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-FBP2 antibody produced in rabbit - HPA012513 from Sigma-Aldrich Prices $429.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-FBP2 antibody produced in rabbit - SAB2100776 from Sigma-Aldrich Prices $347.50 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-FBP2 antibody produced in rabbit - SAB1411566 from Sigma-Aldrich Prices $347.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-FBP2 antibody produced in rabbit - SAB2105711 from Sigma-Aldrich Prices $347.50 Sizes 100 µl Host Rabbit Clonality Polyclonal

FBP2 antibody - middle region (ARP47813_P050) - ARP47813_P050 from Aviva Systems Biology Prices $289.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

FBP2 antibody - middle region (ARP48089_P050) - ARP48089_P050 from Aviva Systems Biology Prices $289.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

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