HRH4

Gene Symbol HRH4
Entrez Gene 59340
Alt Symbol AXOR35, BG26, GPCR105, GPRv53, H4, H4R, HH4R
Species Human
Gene Type protein-coding
Description histamine receptor H4
Other Description G-protein coupled receptor 105|SP9144|histamine H4 receptor|pfi-013
Swissprots B2KJ48 Q9GZQ0 Q4G0I6 B0YJ19 Q9H3N8
Accessions ACA05997 EAX01189 Q9H3N8 AB044934 BAB13698 AB045370 BAB20091 AF307973 AAG32052 AF312230 AAK12081 AF325356 AAL01684 AF329449 AAK43542 AJ298292 CAC83493 AY008280 AAL09297 AY136745 AAN01271 BC069136 AAH69136 BC112348 AAI12349 DQ835186 ABI54174 DQ835187 ABI54175 XM_011526133 XP_011524435 XM_011526134 XP_011524436 NM_001143828 NP_001137300 NM_001160166 NP_001153638 NM_021624 NP_067637
Function The H4 subclass of histamine receptors could mediate the histamine signals in peripheral tissues. Displays a significant level of constitutive activity (spontaneous activity in the absence of agonist). {ECO:0000269|PubMed:12503632}.
Subcellular Location Cell membrane; Multi-pass membrane protein.
Tissue Specificity Expressed primarily in the bone marrow and eosinophils. Shows preferential distribution in cells of immunological relevance such as T-cells, dendritic cells, monocytes, mast cells, neutrophils. Also expressed in a wide variety of peripheral tissues, including the heart, kidney, liver, lung, pancreas, skeletal muscle, prostate, small intestine, spleen, testis, colon, fetal liver and lymph node. {ECO:0000269|PubMed:12503632}.
Top Pathways Neuroactive ligand-receptor interaction

HRH4 overexpression lysate - LY411975 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

Panoply™ Human HRH4 Knockdown Stable Cell Line - CSC-DC007252 from Creative biogene

Category Cell Line
Species Human
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