HRH4

Gene Symbol HRH4
Entrez Gene 59340
Alt Symbol AXOR35, BG26, GPCR105, GPRv53, H4, H4R, HH4R
Species Human
Gene Type protein-coding
Description histamine receptor H4
Other Description G-protein coupled receptor 105|SP9144|histamine H4 receptor|pfi-013
Swissprots B2KJ48 Q9GZQ0 Q4G0I6 B0YJ19 Q9H3N8
Accessions ACA05997 EAX01189 Q9H3N8 AB044934 BAB13698 AB045370 BAB20091 AF307973 AAG32052 AF312230 AAK12081 AF325356 AAL01684 AF329449 AAK43542 AJ298292 CAC83493 AY008280 AAL09297 AY136745 AAN01271 BC069136 AAH69136 BC112348 AAI12349 DQ835186 ABI54174 DQ835187 ABI54175 XM_011526133 XP_011524435 XM_011526134 XP_011524436 NM_001143828 NP_001137300 NM_001160166 NP_001153638 NM_021624 NP_067637
Function The H4 subclass of histamine receptors could mediate the histamine signals in peripheral tissues. Displays a significant level of constitutive activity (spontaneous activity in the absence of agonist). {ECO:0000269|PubMed:12503632}.
Subcellular Location Cell membrane; Multi-pass membrane protein.
Tissue Specificity Expressed primarily in the bone marrow and eosinophils. Shows preferential distribution in cells of immunological relevance such as T-cells, dendritic cells, monocytes, mast cells, neutrophils. Also expressed in a wide variety of peripheral tissues, including the heart, kidney, liver, lung, pancreas, skeletal muscle, prostate, small intestine, spleen, testis, colon, fetal liver and lymph node. {ECO:0000269|PubMed:12503632}.
Top Pathways Neuroactive ligand-receptor interaction

Histamine H4 Receptor CRISPR/Cas9 KO Plasmid (h) - sc-402430 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Histamine H4 Receptor HDR Plasmid (h) - sc-402430-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Histamine H4 Receptor Double Nickase Plasmid (h) - sc-402430-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Histamine H4 Receptor Double Nickase Plasmid (h2) - sc-402430-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Histamine H4 Receptor CRISPR Activation Plasmid (h) - sc-402430-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Histamine H4 Receptor CRISPR Activation Plasmid (h2) - sc-402430-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Histamine H4 Receptor Lentiviral Activation Particles (h) - sc-402430-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Histamine H4 Receptor Lentiviral Activation Particles (h2) - sc-402430-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Histamine H4 Receptor siRNA (h) - sc-40025 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Histamine H4 Receptor shRNA Plasmid (h) - sc-40025-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Histamine H4 Receptor shRNA (h) Lentiviral Particles - sc-40025-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Histamine H4 R RNAi - H00059340-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU153641 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN10300 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10300 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR11434 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr11434

HRH4 siRNA (Human) - CRJ1773 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

HRH4 - MBS8219017 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Histamine H4 Receptor CRISPR/Cas9 KO Plasmid (h2) - sc-402430-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Histamine H4 Receptor HDR Plasmid (h2) - sc-402430-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

shRNA set against Human H4 (NM_021624.3) - SHH310025 from Creative biogene

Category siRNA
Species Reactivities Human

Human HRH4 siRNA - orb272274 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

HRH4 shRNA Plasmid (Human) - CHJ1773 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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