PDE10A

Gene Symbol	PDE10A
Entrez Gene	10846
Alt Symbol	HSPDE10A
Species	Human
Gene Type	protein-coding
Description	phosphodiesterase 10A
Other Description	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A|dJ416F21.1 (phosphodiesterase 10A)|phosphodiesterase 10A1 (PDE10A1)
Swissprots	Q9Y5T1 Q9HCP9 Q9Y233 Q9NTV4 Q6FHX1 Q9ULW9
Accessions	BAB16383 BAB92963 CAJ29925 EAW47546 Q9Y233 AB020593 BAA78034 AB026816 BAA84467 AF127479 AAD32595 AF127480 AAD32596 AI632009 AK021956 AK098543 AK297555 BAG59948 BC104858 AAI04859 BC104860 AAI04861 BC143297 BC143301 CR536567 CAG38804 DR000181 XM_006715321 XP_006715384 XM_011535387 XP_011533689 XM_011535388 XP_011533690 XM_011535389 XP_011533691 XM_011535390 XP_011533692 XM_011535391 XP_011533693 XM_011535392 XP_011533694 XM_011535393 XP_011533695 NM_001130690 NP_001124162 NM_006661 NP_006652 NR_045597
Function	Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. Can hydrolyze both cAMP and cGMP, but has higher affinity for cAMP and is more efficient with cAMP as substrate. {ECO:0000269|PubMed:17389385}.
Subcellular Location	Cytoplasm. Note=Located mostly to soluble cellular fractions.
Tissue Specificity	Abundant in the putamen and caudate nucleus regions of brain and testis, moderately expressed in the thyroid gland, pituitary gland, thalamus and cerebellum.
Top Pathways	Morphine addiction, Purine metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human PDE10A ELISA Kit (Sandwich ELISA) - LS-F8309 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.104 ng/ml Range 0.313-20 ng/ml

Human Phosphodiesterase 10A ELISA Kit - abx152726 from Abbexa Category ELISA Kit Sensitivity 0.104 ng/ml Range 0.313 ng/ml - 20 ng/ml

CAMP and cAMP-inhibited cGMP 3', 5'-cyclic phosphodiesterase 10A (PDE10A), Human, ELISA kit - CSB-EL017681HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, PDE10A, Human, ELISA Kit - E1158h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 0.312-20 ng/mL

Phosphodiesterase 10A (PDE10A), Human, ELISA Kit - SEF656Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.104ng/mL Range 0.312-20ng/mL

cGMP, ELISA Kit - MBS2515746 from MyBioSource Category ELISA Kit Prices $410.00, $490.00, $2,040.00, $3,590.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.469pmol/mL Range 0.781--50pmol/mL

cGMP, ELISA Kit - MBS2515804 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.938ng/mL Range 1.563-100ng/mL

cGMP, ELISA Kit - MBS2516175 from MyBioSource Category ELISA Kit Prices $445.00 Sizes 96 -strip-wells Sensitivity 0.469pmol/mL Range 0.781-50pmol/mL

cAMP and cAMP-inhibited cGMP 3', 5'-cyclic phosphodiesterase 10A (PDE10A) , ELISA Kit - MBS706362 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 31.25 pg/ml Range 125 pg/ml-8000 pg/ml

Phosphodiesterase 10A, ELISA Kit - MBS096514 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Phosphodiesterase 10A, ELISA Kit - MBS080915 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Phosphodiesterase 10A, ELISA Kit - MBS103967 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Phosphodiesterase 10A, ELISA Kit - MBS067377 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Phosphodiesterase 10A, ELISA Kit - MBS062259 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Phosphodiesterase 10A, ELISA Kit - MBS056986 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Phosphodiesterase 10A, ELISA Kit - MBS105709 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Phosphodiesterase 10A (PDE10A), ELISA Kit - MBS2022772 from MyBioSource Category ELISA Kit Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of human PDE10A is typically less than 0.104ng/mL. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined by adding two standard deviations to the mean optical density value of twenty zero standard replicates and calculating the corresponding concentration. Range 0.312-20ng/mL

ELISA Kit for Phosphodiesterase 10A (PDE10A) - SEF656Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.104ng/mL. Range 0.313-20ng/mL The standard curve concentrations used for the ELISA’s were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

Human cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (PDE10A) E - CSB-EL017681HU from Cusabio Sensitivity 31.25 pg/ml Range 125 pg/ml-8000 pg/ml

Mouse PDE10A ELISA Kit (Custom ELISA) - LS-F16244 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 0.313-20 ng/ml

Human PDE10A ELISA Kit (Custom ELISA) - LS-F16243 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 0.313-20 ng/ml

Rat PDE10A ELISA Kit (Custom ELISA) - LS-F16242 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 0.313-20 ng/ml

Human Phosphodiesterase 10A (PDE10A) ELISA Kit - EKU06586 from Biomatik Category ELISA Kit Prices $735.00, $3,234.00, $5,880.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 0.104 ng/mL Range 0.312-20 ng/mL

Human cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A ELISA Kit - abx250591 from Abbexa Category ELISA Kit Range 0.312 ng/ml - 20 ng/ml

Phosphodiesterase 10A (PDE10A), Human, ELISA Kit - DL-PDE10A-Hu from ARP American Research Products Category ELISA Kit Prices $655.00 Sizes 96 t Range 0.312-20 ng/mL

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