PDE10A

Gene Symbol	PDE10A
Entrez Gene	10846
Alt Symbol	HSPDE10A
Species	Human
Gene Type	protein-coding
Description	phosphodiesterase 10A
Other Description	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A|dJ416F21.1 (phosphodiesterase 10A)|phosphodiesterase 10A1 (PDE10A1)
Swissprots	Q9Y5T1 Q9HCP9 Q9Y233 Q9NTV4 Q6FHX1 Q9ULW9
Accessions	BAB16383 BAB92963 CAJ29925 EAW47546 Q9Y233 AB020593 BAA78034 AB026816 BAA84467 AF127479 AAD32595 AF127480 AAD32596 AI632009 AK021956 AK098543 AK297555 BAG59948 BC104858 AAI04859 BC104860 AAI04861 BC143297 BC143301 CR536567 CAG38804 DR000181 XM_006715321 XP_006715384 XM_011535387 XP_011533689 XM_011535388 XP_011533690 XM_011535389 XP_011533691 XM_011535390 XP_011533692 XM_011535391 XP_011533693 XM_011535392 XP_011533694 XM_011535393 XP_011533695 NM_001130690 NP_001124162 NM_006661 NP_006652 NR_045597
Function	Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. Can hydrolyze both cAMP and cGMP, but has higher affinity for cAMP and is more efficient with cAMP as substrate. {ECO:0000269|PubMed:17389385}.
Subcellular Location	Cytoplasm. Note=Located mostly to soluble cellular fractions.
Tissue Specificity	Abundant in the putamen and caudate nucleus regions of brain and testis, moderately expressed in the thyroid gland, pituitary gland, thalamus and cerebellum.
Top Pathways	Morphine addiction, Purine metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human PDE10A full length protein - ab198428 from Abcam Category Protein Prices $1,250.00 Sizes 10 µg Source Baculovirus infected sf9 cells Species Human

Active human PDE10A protein fragment - ab101116 from Abcam Category Protein Prices $302.00, $410.00 Sizes 5 µg, 10 µg Source Baculovirus Species Human

Active mouse PDE10A full length protein - ab79743 from Abcam Category Protein Prices $302.00 Sizes 5 µg Source Baculovirus infected sf9 cells Species Mouse

Active PDE10A protein fragment - ab80327 from Abcam Category Protein Prices $466.00 Sizes 5 µg Source Baculovirus infected sf9 cells

Human PDE10A protein fragment - ab153135 from Abcam Category Protein Source Wheat germ Species Human

PDE10A full length protein - ab54064 from Abcam Category Protein Source Baculovirus infected sf9 cells

PDE10A peptide - ab185003 from Abcam Category Peptide

Recombinant Human PDE10A Protein - H00010846-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

PDE10A - H00010846-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

PDE10A - H00010846-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

PDE10A Control Peptide - AP10255CP-N from Acris Antibodies Category Peptide Prices $255.00 Sizes 100 µg

PDE10A control peptide - AP10256CP-N from Acris Antibodies Category Peptide Prices $235.00 Sizes 250 µg

PDE10A fusion protein - ag12892 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

PDE10A fusion protein - Ag12771 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

PDE10A2 Active Human Recombinant Protein - GWB-A6F078 from Genway Biotech Category Protein Prices $600.00 Sizes 10 µg Species Human

PDE10A1 Active Human Recombinant Protein - GWB-2AAF78 from Genway Biotech Category Protein Prices $600.00 Sizes 10 µg Species Human

Recombinant Human Phosphodiesterase 10A, GST-tagged - PDE10A-440H from Creative Biomart Category Protein Source Sf9 cell.

Recombinant Human PDE10A, GST-tagged - PDE10A-1610H from Creative Biomart Category Protein Source Sf9 insect cells Species Human

Recombinant Phosphodiesterase 10A (PDE10A) - RPF656Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Phosphodiesterase 10A (PDE10A) - RPF656Hu01 from Cloud-clone Category Protein Source E.coli Species Human

hPDE10A-HEK293 Recombinant Cell line - GWB-PS2038 from Genway Biotech Category Protein Prices $10,776.00 Sizes 1x10cells (6) Species Human

PDE10A (transcript variant 2) - TP311181 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Phosphodiesterase 10A, Recombinant Protein - MBS635985 from MyBioSource Category Protein Prices $715.00 Sizes 10 µg Source Sf9 insect cells

Phosphodiesterase 10A, Recombinant Protein - MBS637379 from MyBioSource Category Protein Prices $715.00 Sizes 10 µg

PDE10A Peptide, Human - M34GP11494H from Creative Peptides Category Peptide Source Synthetic. Species Human

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