PDE10A

Gene Symbol PDE10A
Entrez Gene 10846
Alt Symbol HSPDE10A
Species Human
Gene Type protein-coding
Description phosphodiesterase 10A
Other Description cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A|dJ416F21.1 (phosphodiesterase 10A)|phosphodiesterase 10A1 (PDE10A1)
Swissprots Q9Y5T1 Q9HCP9 Q9Y233 Q9NTV4 Q6FHX1 Q9ULW9
Accessions BAB16383 BAB92963 CAJ29925 EAW47546 Q9Y233 AB020593 BAA78034 AB026816 BAA84467 AF127479 AAD32595 AF127480 AAD32596 AI632009 AK021956 AK098543 AK297555 BAG59948 BC104858 AAI04859 BC104860 AAI04861 BC143297 BC143301 CR536567 CAG38804 DR000181 XM_006715321 XP_006715384 XM_011535387 XP_011533689 XM_011535388 XP_011533690 XM_011535389 XP_011533691 XM_011535390 XP_011533692 XM_011535391 XP_011533693 XM_011535392 XP_011533694 XM_011535393 XP_011533695 NM_001130690 NP_001124162 NM_006661 NP_006652 NR_045597
Function Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. Can hydrolyze both cAMP and cGMP, but has higher affinity for cAMP and is more efficient with cAMP as substrate. {ECO:0000269|PubMed:17389385}.
Subcellular Location Cytoplasm. Note=Located mostly to soluble cellular fractions.
Tissue Specificity Abundant in the putamen and caudate nucleus regions of brain and testis, moderately expressed in the thyroid gland, pituitary gland, thalamus and cerebellum.
Top Pathways Morphine addiction, Purine metabolism

PDE10A CRISPR/Cas9 KO Plasmid (h) - sc-403981 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PDE10A HDR Plasmid (h) - sc-403981-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PDE10A Double Nickase Plasmid (h) - sc-403981-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PDE10A Double Nickase Plasmid (h2) - sc-403981-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PDE10A CRISPR Activation Plasmid (h) - sc-403981-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PDE10A CRISPR Activation Plasmid (h2) - sc-403981-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PDE10A Lentiviral Activation Particles (h) - sc-403981-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PDE10A Lentiviral Activation Particles (h2) - sc-403981-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PDE10A siRNA (h) - sc-62761 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PDE10A shRNA Plasmid (h) - sc-62761-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PDE10A shRNA (h) Lentiviral Particles - sc-62761-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PDE10A RNAi - H00010846-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU075691 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN16528 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16528 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

PDE10A siRNA (Human) - CRH7386 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Human PDE10A siRNA - orb267888 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PDE10A shRNA Plasmid (Human) - CHH7386 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
Search more